CENTRO DE INVESTIGACION DEL CANCER

  • Laboratorio 13

Idoia García Ramírez


Biography
Idoia García Ramírez
Contact

Centro de Investigación del Cáncer (Universidad de Salamanca-CSIC)
Campus Universitario Miguel de Unamuno s/n
37007 Salamanca
SPAIN

Areas of Research
Projects
Publications

(*) Means equal contribution as senior authors.



2019
2018

Lmo2 expression defines tumor cell identity during T-cell leukemogenesis.

García-Ramírez I, Bhatia S, Rodríguez-Hernández G, González-Herrero I, Walter C, González de Tena-Dávila S, Parvin S, Haas O, Woessmann W, Stanulla M, Schrappe M, Dugas M, Natkunam Y, Orfao A, Domínguez V, Pintado B, Blanco O, Alonso-López D, De Las Rivas J, Martín-Lorenzo A, Jiménez R, García Criado FJ, García Cenador MB, Lossos IS, Vicente-Dueñas C, Borkhardt A, Hauer J, Sánchez-García I, 
EMBO J.; 2018; 37(14); e98783; 29880602

Loss of Pax5 Exploits Sca1-BCR-ABL Susceptibility to Confer the Metabolic Shift Essential for pB-ALL.

Martín-Lorenzo A, Auer F, Chan LN, García-Ramírez I, González-Herrero I, Rodríguez-Hernández G, Bartenhagen C, Dugas M, Gombert M, Ginzel S, Blanco O, Orfao A, Alonso-López D, Rivas JL, De Las Rivas J, Begoña García-Cenador M, García-Cenador MB, Javier García Criado F, García-Criado FJ, Müschen M, Sánchez-García I, Borkhardt A, Vicente-Dueñas C, Hauer J, 
Cancer Res.; 2018; 78(10); 2669-267; 29490943


2017

Infection Exposure Promotes Precursor B-cell Leukemia via Impaired H3K4 Demethylases.

Rodríguez-Hernández G, Hauer J, Martín-Lorenzo A, Schafer D, Bartenhagen C, García-Ramírez I, Auer F, González-Herrero I, Ruiz-Roca L, Gombert M, Okpanyi V, Fischer U, Chen C, Dugas M, Bhatia S, Linka RM, Garcia-Suquia M, Rascón-Trincado MV, Garcia-Sanchez A, Blanco O, García-Cenador MB, García-Criado FJ, Cobaleda C, Alonso-López D, De Las Rivas J, Müschen M, Vicente-Dueñas C, Sánchez-García I, Borkhardt A, 
Cancer Res.; 2017; 77(16); 4365-437; 28630052

loss cooperates with overexpression to promote lymphoma in mice.

García-Ramírez I, Tadros S, González-Herrero I, Martín-Lorenzo A, Rodríguez-Hernández G, Moore D, Ruiz-Roca L, Blanco O, Alonso-López D, Rivas JL, De Las Rivas J, Hartert K, Duval R, Klinkebiel D, Bast M, Vose J, Lunning M, Fu K, Greiner T, Rodrigues-Lima F, Jiménez R, Criado FJG, García Criado FJ, Cenador MBG, García Cenador MB, Brindle P, Vicente-Dueñas C, Alizadeh A, Sánchez-García I, Green MR, 
Blood; 2017; 129(19); 2645-265; 28288979


2015

Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.

Martín-Lorenzo A, Hauer J, Vicente-Duenas C, Vicente-Dueñas C, Auer F, González-Herrero I, García-Ramírez I, Ginzel S, Thiele R, Constantinescu SN, Bartenhagen C, Dugas M, Gombert M, Schafer D, Blanco O, Mayado A, Orfao A, Alonso-López D, Rivas Jde L, De Las Rivas J, Cobaleda C, García-Cenador MB, García-Criado FJ, Sánchez-García I, Borkhardt A, 
Cancer Discov; 2015; 5(12); 1328-43; 26408659


2014

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.

Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sánchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I, 
Nat Commun; 2014; 5(); 3904; 24887457


2013
Patents
Group
  • Silvia Alemán Arteaga Silvia Alemán Arteaga

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  • Idoia García Ramírez Idoia García Ramírez

    Idoia García Ramírez

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  • Sara González de Tena-Dávila Sara González de Tena-Dávila

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  • LIDIA  IGLESIAS BAYO LIDIA IGLESIAS BAYO

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  • Andrea López Álvarez de Neyra Andrea López Álvarez de Neyra

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  • Guillermo Rodríguez Hernández Guillermo Rodríguez Hernández

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  • Isidro Sánchez García Isidro Sánchez García

    Isidro Sánchez García

    Experimental and Translational Oncology Laboratory: Stem Cells, Cancer Stem Cells and Cancer

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    Dr. Isidro Sánchez-García
    Senior Staff Researcher CSIC, Laboratorio 13, Instituto de Biologia Molecular y Celular del Cancer (IBMCC), CSIC/Universidad de Salamanca, Campus Unamuno s/n, 37007-Salamanca, (Spain).

    923 294 813
    923 294813
    isg(arroba)usal(.)es

    Laboratorio 13, Instituto de Biologia Molecular y Celular del Cancer (IBMCC), CSIC/Universidad de Salamanca, Campus Unamuno s/n, 37007-Salamanca, (Spain).


    Biography

    Isidro Sánchez-García’s biographical sketch

    Isidro Sánchez-García is a Senior Staff Scientist at the Instituto de Biologia Molecular y Celular del Cancer (IBMCC) of the Spanish National Research Council (CSIC). He learnt and practiced Medicine before completing his Ph.D. at University of Salamanca. Isidro was a postdoctoral fellow for five years at the Medical Research Council’s Laboratory of Molecular Biology in Cambridge (UK) before appointment to his current position in 1997.

    My research is focused on attaining a better understanding of the initiation, maintenance, and progression of leukemia, toward improving current treatment and/or prevention strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.

    I hope to apply this knowledge to change the way we approach leukemia, from diagnosis and treatment to prevention first.

    This work has allowed to establish both a pioneer relationship between stem cells and cancer and a causal link between infection and leukemia. The novel scientific achievements and ideas have not only resulted in high quality publications during his career but also they have crystallized into the first European patent granted in the field of Leukemia/Cancer Stem Cells.

    This work has been awarded by the International Carreras Foundation (http://www.carrerasfoundation.org/fellow_bio.htm), and by the Eurosystem prize in 2010.

    His research group hopes this investigation will result not only in new concepts in cancer biology and development, but also it  will provide the basis for the development of both a new strategy in cancer therapy and new methods for assessing treatment efficacy.

    Isidro

    POSICIONES DE MASTER Y TESIS:
    El grupo tiene abierta dos posiciones anuales para nuevos candidatos interesados en trabajar con nosotros. Se require un grado biomédico y un expediente superior a 2.8. Ponerse en contacto con el investigador principal.

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  • Laura Sánchez Vázquez Laura Sánchez Vázquez

    Laura Sánchez Vázquez

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  • Zuzanna Urban Zuzanna Urban

    Zuzanna Urban

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  • Carolina Vicente Dueñas Carolina Vicente Dueñas

    Carolina Vicente Dueñas

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