Cabergoline as a Novel Strategy for Post-Pregnancy Breast Cancer Prevention in Mice and Human.

García-Sancha N, Corchado-Cobos R, Blanco-Gómez A, Cunillera Puértolas O, Marzo-Castillejo M, Castillo-Lluva S, Alonso-López D, De Las Rivas J, Pozo J, Orfao A, Valero-Juan L, Patino-Alonso C, Perera D, Venkitaraman AR, Mao JH, Chang H, Mendiburu-Eliçabe M, González-García P, Caleiras E, Peset I, Cenador MBG, García-Criado FJ, Perez-Losada J, 
Res Sq; 2024; (); rs.3.rs-3854490; 38405932

Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice.

Isidro-Hernández M, Casado-García A, Oak N, Alemán-Arteaga S, Ruiz-Corzo B, Martínez-Cano J, Mayado A, Sánchez EG, Blanco O, Gaspar ML, Orfao A, Alonso-López D, De Las Rivas J, Riesco S, Prieto-Matos P, González-Murillo Á, Criado FJG, Cenador MBG, Ramírez-Orellana M, de Andrés B, Vicente-Dueñas C, Cobaleda C, Nichols KE, Sánchez-García I, 
Nat Commun; 2023; 14(1); 5159; 37620322

Clinical, Histopathologic and Genetic Features of Rhabdoid Meningiomas.

Garrido Ruiz PA, González-Tablas M, Pasco Peña A, Zelaya Huerta MV, Ortiz J, Otero A, Corchete LA, Ludeña MD, Caballero Martínez MC, Córdoba Iturriagagoitia A, Fernández IC, González-Carreró Fojón J, Hernández Laín A, Orfao A, Tabernero MD, 
Int J Mol Sci; 2023; 24(2); 1116; 36674634

Transient inhibition of the JAK/STAT pathway prevents B-ALL development in genetically predisposed mice.

Casado-García A, Isidro-Hernández M, Oak N, Mayado A, Mann-Ran C, Raboso-Gallego J, Alemán-Arteaga S, Buhles A, Sterker D, Sánchez EG, Martínez-Cano J, Blanco O, Orfao A, Alonso-López D, De Las Rivas J, Riesco S, Prieto-Matos P, González-Murillo Á, Garcia Criado FJJ, García Cenador MB, Radimerski T, Ramírez-Orellana M, Cobaleda C, Yang JJ, Vicente-Dueñas C, Weiss A, Nichols KE, Sánchez-García I, 
Cancer Res; 2022; ; canres.3386.2021; 35131871

Overcoming Resistance to Immunotherapy in Advanced Cutaneous Squamous Cell Carcinoma.

García-Sancha N, Corchado-Cobos R, Bellido-Hernández L, Román-Curto C, Cardeñoso-Álvarez E, Perez-Losada J, Orfao A, Cañueto J, 
Cancers (Basel); 2021; 13(20); 5134; 34680282

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma.

Goicoechea I, Puig N, Cedena MT, Burgos L, Cordón L, Vidriales MB, Flores-Montero J, Gutiérrez NC, Calasanz MJ, Ramos MM, Lara-Astiaso D, Vilas-Zornoza A, Alignani D, Rodriguez I, Sarvide S, Alameda D, Garcés JJ, Rodriguez S, Fresquet V, Celay J, García-Sanz R, Martinez-Lopez J, Oriol A, Ríos R, Martín-Sánchez J, Martinez-Martinez R, Sarra J, Hernández MT, de la Rubia J, Krsnik I, Moraleda JM, Palomera L, Bargay J, Martínez-Climent JA, Orfao A, Rosiñol L, Mateos MV, Lahuerta JJ, Bladé J, San Miguel J, Paiva B, 
Blood; 2021; 137(1); 49-60; 32693406

Inhibition of inflammatory signaling in Pax5 mutant cells mitigates B-cell leukemogenesis.

Isidro-Hernández M, Mayado A, Casado-García A, Martínez-Cano J, Palmi C, Fazio G, Orfao A, Ribera J, Ribera JM, Zamora L, Raboso-Gallego J, Blanco O, Alonso-López D, De Las Rivas J, Jiménez R, García Criado FJ, García Cenador MB, Ramírez-Orellana M, Cazzaniga G, Cobaleda C, Vicente-Dueñas C, Sánchez-García I, 
Sci Rep; 2020; 10(1); 19189; 33154497

Comparison of next-generation sequencing (NGS) and next-generation flow (NGF) for minimal residual disease (MRD) assessment in multiple myeloma.

Medina A, Puig N, Flores-Montero J, Jimenez C, Sarasquete ME, García-Álvarez M, Prieto-Conde I, Chillón C, Alcoceba M, Gutiérrez NC, Oriol A, Rosinol L, Bladé J, Gironella M, Hernández MT, González-Calle V, Cedena MT, Paiva B, San-Miguel JF, Lahuerta JJ, Mateos MV, Martinez-Lopez J, Orfao A, González M, García-Sanz R, 
Blood Cancer J; 2020; 10(10); 108; 33127891

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma.

Perez C, Botta C, Zabaleta A, Puig N, Cedena MT, Goicoechea I, Alameda D, San José-Eneriz E, Merino J, Rodríguez-Otero P, Maia C, Alignani D, Maiso P, Manrique I, Lara-Astiaso D, Vilas-Zornoza A, Sarvide S, Riillo C, Rossi M, Rosiñol L, Oriol A, Blanchard MJ, Ríos R, Sureda A, Martín J, Martínez R, Bargay J, de la Rubia J, Hernández MT, Martinez-Lopez J, Orfao A, Agirre X, Prosper F, Mateos MV, Lahuerta JJ, Bladé J, San-Miguel JF, Paiva B, 
Blood; 2020; 136(2); 199-209; 32325491

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID.

Rodríguez-Hernández G, Opitz FV, Delgado P, Walter C, Álvarez-Prado AF, González-Herrero I, Auer F, Fischer U, Janssen S, Bartenhagen C, Raboso-Gallego J, Casado-García A, Orfao A, Blanco O, Alonso-López D, Rivas JL, Tena-Dávila SG, Müschen M, Dugas M, Criado FJG, Cenador MBG, Vicente-Dueñas C, Hauer J, Ramiro AR, Sánchez-García I, Borkhardt A, 
Nat Commun; 2019; 10(1); 5563; 31804490

Lmo2 expression defines tumor cell identity during T-cell leukemogenesis.

García-Ramírez I, Bhatia S, Rodríguez-Hernández G, González-Herrero I, Walter C, González de Tena-Dávila S, Parvin S, Haas O, Woessmann W, Stanulla M, Schrappe M, Dugas M, Natkunam Y, Orfao A, Domínguez V, Pintado B, Blanco O, Alonso-López D, De Las Rivas J, Martín-Lorenzo A, Jiménez R, García Criado FJ, García Cenador MB, Lossos IS, Vicente-Dueñas C, Borkhardt A, Hauer J, Sánchez-García I, 
EMBO J.; 2018; 37(14); e98783; 29880602

Loss of Pax5 Exploits Sca1-BCR-ABL Susceptibility to Confer the Metabolic Shift Essential for pB-ALL.

Martín-Lorenzo A, Auer F, Chan LN, García-Ramírez I, González-Herrero I, Rodríguez-Hernández G, Bartenhagen C, Dugas M, Gombert M, Ginzel S, Blanco O, Orfao A, Alonso-López D, Rivas JL, De Las Rivas J, Begoña García-Cenador M, García-Cenador MB, Javier García Criado F, García-Criado FJ, Müschen M, Sánchez-García I, Borkhardt A, Vicente-Dueñas C, Hauer J, 
Cancer Res.; 2018; 78(10); 2669-267; 29490943

Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia.

García-Barchino MJ, Sarasquete ME, Panizo C, Morscio J, Martinez A, Alcoceba M, Fresquet V, Gonzalez-Farre B, Paiva B, Young KH, Robles EF, Roa S, Celay J, Larrayoz M, Rossi D, Gaidano G, Montes-Moreno S, Piris MA, Balanzategui A, Jimenez C, Rodriguez I, Calasanz MJ, Larrayoz MJ, Segura V, García-Muñóz R, Rabasa MP, Yi S, Li J, Zhang M, Xu-Monette ZY, Puig-Moron N, Orfao A, Böttcher S, Hernandez-Rivas JM, Miguel JS, Prosper F, Tousseyn T, Sagaert X, González M, Martínez-Climent JA, 
J. Pathol.; 2018; 245(1); 61-73; 29464716

Prognostic impact of a novel gene expression profile classifier for the discrimination between metastatic and non-metastatic primary colorectal cancer

Gutiérrez ML, Corchete LA, Sarasquete ME, Del Mar Abad M, Bengoechea O, Fermiñán E, Anduaga MF, Del Carmen S, Iglesias M, Esteban C, Angoso M, Alcazar JA, García J, Orfao A, Muñoz-Bellvis L, Sayagués JM, 
Oncotarget; 2017; 8(64); 107685-107700; 29296198

Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.

Valent P, Akin C, Hartmann K, Nilsson G, Reiter A, Hermine O, Sotlar K, Sperr WR, Escribano L, George TI, Kluin-Nelemans HC, Ustun C, Triggiani M, Brockow K, Gotlib J, Orfao A, Schwartz LB, Broesby-Olsen S, Bindslev-Jensen C, Kovanen PT, Galli SJ, Austen KF, Arber DA, Horny HP, Arock M, Metcalfe DD, 
Cancer Res.; 2017; 77(6); 1261-127; 28254862

A Next-Generation Sequencing Strategy for Evaluating the Most Common Genetic Abnormalities in Multiple Myeloma.

Jimenez C, Jara-Acevedo M, Corchete LA, Castillo D, Ordóñez GR, Sarasquete ME, Puig N, Martinez-Lopez J, Prieto-Conde MI, García-Álvarez M, Chillón MC, Balanzategui A, Alcoceba M, Oriol A, Rosiñol L, Palomera L, Teruel AI, Lahuerta JJ, Bladé J, Mateos MV, Orfao A, San Miguel JF, González M, Gutiérrez NC, García-Sanz R, 
J Mol Diagn; 2017; 19(1); 99-106; 27863261

Expression profile of novel cell surface molecules on different subsets of human peripheral blood antigen-presenting cells.

Damasceno D, Andrés MP, van den Bossche WB, Flores-Montero J, de Bruin S, Teodosio C, van Dongen JJ, Orfao A, Almeida J, 
Clin Transl Immunology; 2016; 5(9); e100; 27766148

Genomic characterization of liver metastases from colorectal cancer patients.

Sayagués JM, Corchete LA, Gutiérrez ML, Sarasquete ME, Del Mar Abad M, Bengoechea O, Fermiñán E, Anduaga MF, Del Carmen S, Iglesias M, Esteban C, Angoso M, Alcazar JA, García J, Orfao A, Muñoz-Bellvis L, 
Oncotarget; 2016; 7(45); 72908-72922; 27662660

Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.

Martín-Lorenzo A, Hauer J, Vicente-Duenas C, Vicente-Dueñas C, Auer F, González-Herrero I, García-Ramírez I, Ginzel S, Thiele R, Constantinescu SN, Bartenhagen C, Dugas M, Gombert M, Schafer D, Blanco O, Mayado A, Orfao A, Alonso-López D, Rivas Jde L, De Las Rivas J, Cobaleda C, García-Cenador MB, García-Criado FJ, Sánchez-García I, Borkhardt A, 
Cancer Discov; 2015; 5(12); 1328-43; 26408659

Integration of Proteomics and Transcriptomics Data Sets for the Analysis of a Lymphoma B-Cell Line in the Context of the Chromosome-Centric Human Prot

Díez P, Droste C, Dégano RM, González-Muñoz M, Ibarrola N, Pérez-Andrés M, Garin-Muga A, Segura V, Marko-Varga G, LaBaer J, Orfao A, Corrales FJ, De Las Rivas J, Fuentes M, 
J. Proteome Res.; 2015; 14(9); 3530-40; 26216070

A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.

Castillo-Lluva S, Hontecillas-Prieto L, Blanco-Gómez A, Del Mar Sáez-Freire M, García-Cenador B, García-Criado J, Pérez-Andrés M, Orfao A, Cañamero M, Mao JH, Gridley T, Castellanos-Martín A, Perez-Losada J, 
Oncogene; 2015; 34(36); 4777-90; 26096931

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.

Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sánchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I, 
Nat Commun; 2014; 5(); 3904; 24887457

Identification of a characteristic copy number alteration profile by high-resolution single nucleotide polymorphism arrays associated with metastatic

González-González M, Fontanillo C, Abad MM, Gutiérrez ML, Mota I, Bengoechea O, Santos-Briz A, Blanco O, Fonseca E, Ciudad J, Fuentes M, De Las Rivas J, Alcazar JA, García J, Muñoz-Bellvis L, Orfao A, Sayagués JM, 
Cancer; 2014; 120(13); 1948-59; 24668684

Enhanced cytotoxic activity of bile acid cisplatin derivatives by conjugation with gold nanoparticles.

Sánchez-Paradinas S, Pérez-Andrés M, Almendral-Parra MJ, Rodríguez-Fernández E, Millán A, Palacio F, Orfao A, Criado JJ, Fuentes M, 
J. Inorg. Biochem.; 2014; 131(); 8-11; 24239907

Testosterone replacement therapy in hypogonadal men is associated with increased expression of LAMP-2 (CD107b) by circulating monocytes and dendritic

Corrales JJ, Almeida M, Martín-Martín L, Miralles JM, Orfao A, 
Clin. Endocrinol. (Oxf); 2014; 80(4); 577-84; 24111582

Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect-induced anaphylaxis shows unique features versus other indolent S

Alvarez-Twose I, Zanotti R, González-de-Olano D, Bonadonna P, Vega A, Matito A, Sánchez-Muñoz L, Morgado JM, Perbellini O, García-Montero A, De Matteis G, Teodosio C, Rossini M, Jara-Acevedo M, Schena D, Mayado A, Zamò A, Mollejo M, Sánchez-López P, Cabañes N, Orfao A, Escribano L, , 
J. Allergy Clin. Immunol.; 2014; 133(2); 520-8; 23921094

Circulating clonotypic B cells in multiple myeloma and monoclonal gammopathy of undetermined significance.

Thiago LS, Pérez-Andrés M, Balanzategui A, Sarasquete ME, Paiva B, Jara-Acevedo M, Bárcena P, Sanchez ML, Almeida J, González M, San Miguel JF, García-Sanz R, Orfao A, 
Haematologica; 2014; 99(1); 155-62; 23872308

Association between mutation of the NF2 gene and monosomy 22 in menopausal women with sporadic meningiomas.

Tabernero M, Jara-Acevedo M, Nieto AB, Caballero AR, Otero A, Sousa P, Gonçalves J, Domingues PH, Orfao A, 
BMC Med. Genet.; 2013; 14(); 114; 24171707

Serum tryptase monitoring in indolent systemic mastocytosis: association with disease features and patient outcome.

Matito A, Morgado JM, Alvarez-Twose I, Sánchez-Muñoz L, Pedreira CE, Jara-Acevedo M, Teodosio C, Sánchez-López P, Fernández-Nuñez E, Moreno-Borque R, García-Montero A, Orfao A, Escribano L, 
PLoS ONE; 2013; 8(10); e76116; 24155887

Protein arrays as tool for studies at the host-pathogen interface.

Manzano-Román R, Dasilva N, Díez P, Díaz-Martín V, Pérez-Sánchez R, Orfao A, Fuentes M, 
J Proteomics; 2013; 94(); 387-400; 24140974

CD30 expression by bone marrow mast cells from different diagnostic variants of systemic mastocytosis.

Morgado JM, Perbellini O, Johnson RC, Teodosio C, Matito A, Alvarez-Twose I, Bonadonna P, Zamò A, Jara-Acevedo M, Mayado A, García-Montero A, Mollejo M, George TI, Zanotti R, Orfao A, Escribano L, Sánchez-Muñoz L, 
Histopathology; 2013; 63(6); 780-7; 24111625

Association between inflammatory infiltrates and isolated monosomy 22/del(22q) in meningiomas.

Domingues PH, Teodosio C, Otero A, Sousa P, Ortiz J, Macias Mdel C, Gonçalves JM, Nieto AB, Lopes MC, de Oliveira C, Orfao A, Tabernero MD, 
PLoS ONE; 2013; 8(10); e74798; 24098347

Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution pro

Paiva B, Paíno T, Sayagués JM, Garayoa M, San-Segundo L, Martín M, Mota I, Sanchez ML, Bárcena P, Aires-Mejia I, Corchete L, Jimenez C, García-Sanz R, Gutiérrez NC, Ocio EM, Mateos MV, Vidriales MB, Orfao A, San Miguel JF, 
Blood; 2013; 122(22); 3591-8; 24072855

Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.

Baltanás FC, Pérez-Andrés M, Ginel-Picardo A, Diaz D, Jimeno D, Liceras-Boillos P, Kortum RL, Samelson LE, Orfao A, Santos E, 
Mol. Cell. Biol.; 2013; 33(22); 4562-78; 24043312

Protein microarrays: technological aspects, applications and intellectual property.

Dasilva N, Díez P, González-González M, Matarraz S, Sayagués JM, Orfao A, Fuentes M, 
Recent Pat Biotechnol; 2013; 7(2); 142-52; 23848276

Combined patterns of IGHV repertoire and cytogenetic/molecular alterations in monoclonal B lymphocytosis versus chronic lymphocytic leukemia.

Henriques A, Rodríguez-Caballero A, Nieto WG, Langerak AW, Criado I, Lecrevisse Q, González M, Pais ML, Paiva A, Almeida J, Orfao A, 
PLoS ONE; 2013; 8(7); e67751; 23844084

Overview of clinical flow cytometry data analysis: recent advances and future challenges.

Pedreira CE, Costa ES, Lecrevisse Q, van Dongen JJ, Orfao A, , 
Trends Biotechnol.; 2013; 31(7); 415-25; 23746659

A multiparameter flow cytometry immunophenotypic algorithm for the identification of newly diagnosed symptomatic myeloma with an MGUS-like signature a

Paiva B, Vidriales MB, Rosiñol L, Martinez-Lopez J, Mateos MV, Ocio EM, Montalbán MA, Cordón L, Gutiérrez NC, Corchete L, Oriol A, Terol MJ, Echeveste MA, de Paz R, de Arriba F, Palomera L, de la Rubia J, Díaz-Mediavilla J, Granell M, Gorosquieta A, Alegre A, Orfao A, Lahuerta JJ, Bladé J, San Miguel JF, , 
Leukemia; 2013; 27(10); 2056-61; 23743858

Clinical practice guidelines for diagnosis, treatment, and follow-up of patients with mantle cell lymphoma. Recommendations from the GEL/TAMO Spanish

Caballero D, Campo E, López-Guillermo A, Martín A, Arranz-Sáez R, Giné E, López A, González-Barca E, Canales MÁ, Gonzalez-Diaz M, Orfao A, 
Ann. Hematol.; 2013; 92(9); 1151-79; 23716187

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.

Vardi A, Dagklis A, Scarfò L, Jelinek D, Newton D, Bennett F, Almeida J, Rodríguez-Caballero A, Allgood S, Lanasa M, Cortelezzi A, Orlandi E, Veronese S, Montillo M, Rawstron A, Shanafelt T, Orfao A, Stamatopoulos K, Ghia P, 
Blood; 2013; 121(22); 4521-8; 23596047

Newly diagnosed adult AML and MPAL patients frequently show clonal residual hematopoiesis.

Fernández C, Santos-Silva MC, López A, Matarraz S, Jara-Acevedo M, Ciudad J, Gutiérrez ML, Sanchez ML, Salvador-Osuna C, Berruezo MJ, Díaz-Arias JÁ, Palomo-Hernández AM, Colado E, González N, Gallardo D, Asensio A, García-Sánchez R, Saldaña R, Cerveró C, Carboné-Bañeres A, Gutiérrez O, Orfao A, 
Leukemia; 2013; 27(11); 2149-56; 23579575

Decreased peripheral blood CD4+/CD25+ regulatory T cells in patients with alcoholic hepatitis.

Almeida J, Polvorosa MA, Gonzalez-Quintela A, Marcos M, Pastor I, Hernandez Cerceño ML, Orfao A, Laso FJ, 
Alcohol. Clin. Exp. Res.; 2013; 37(8); 1361-9; 23550693

Flow cytometry criteria for systemic mastocytosis: bone marrow mast cell counts do not always count.

Sánchez-Muñoz L, Morgado JM, Alvarez-Twose I, Matito A, Escribano L, Teodosio C, Jara-Acevedo M, García-Montero AC, Mayado A, Orfao A, 
Am. J. Clin. Pathol.; 2013; 139(3); 404-6; 23547320

Combined flow cytometric assessment of CD45, HLA-DR, CD34, and CD117 expression is a useful approach for reliable quantification of blast cells in mye

Sandes AF, Kerbauy DM, Matarraz S, Chauffaille Mde L, López A, Orfao A, Yamamoto M, 
Cytometry B Clin Cytom; 2013; 84(3); 157-66; 23475532

Contribution of multiparameter flow cytometry immunophenotyping to the diagnostic screening and classification of pediatric cancer.

Ferreira-Facio CS, Milito C, Botafogo V, Fontana M, Thiago LS, Oliveira E, da Rocha-Filho AS, Werneck F, Forny DN, Dekermacher S, de Azambuja AP, Ferman SE, de Faria PA, Land MG, Orfao A, Costa ES, 
PLoS ONE; 2013; 8(3); e55534; 23472067

Gene expression profile of highly purified bone marrow mast cells in systemic mastocytosis.

Teodosio C, García-Montero AC, Jara-Acevedo M, Sánchez-Muñoz L, Pedreira CE, Alvarez-Twose I, Matarraz S, Morgado JM, Bárcena P, Matito A, Mayado A, Sanchez ML, Diez-Campelo M, Escribano L, Orfao A, 
J. Allergy Clin. Immunol.; 2013; 131(4); 1213-24,; 23403045

International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) & European Competence Network on Mastocytosis (ECNM) consens

Gotlib J, Pardanani A, Akin C, Reiter A, George T, Hermine O, Kluin-Nelemans H, Hartmann K, Sperr WR, Brockow K, Schwartz LB, Orfao A, Deangelo DJ, Arock M, Sotlar K, Horny HP, Metcalfe DD, Escribano L, Verstovsek S, Tefferi A, Valent P, 
Blood; 2013; 121(13); 2393-401; 23325841

Systemic mastocytosis as a risk factor for severe Hymenoptera sting-induced anaphylaxis.

Alvarez-Twose I, Bonadonna P, Matito A, Zanotti R, González-de-Olano D, Sánchez-Muñoz L, Morgado JM, Orfao A, Escribano L, 
J. Allergy Clin. Immunol.; 2013; 131(2); 614-5; 23273956

Nck recruitment to the TCR required for ZAP70 activation during thymic development.

Borroto A, Arellano I, Dopfer EP, Prouza M, Suchànek M, Fuentes M, Orfao A, Schamel WW, Alarcón B, 
J. Immunol.; 2013; 190(3); 1103-12; 23267019

Cytogenetic profiles in multiple myeloma and monoclonal gammopathy of undetermined significance: a study in highly purified aberrant plasma cells.

Schmidt-Hieber M, Gutiérrez ML, Pérez-Andrés M, Paiva B, Rasillo A, Tabernero MD, Sayagués JM, López A, Bárcena P, Sanchez ML, Gutiérrez NC, San Miguel JF, Orfao A, 
Haematologica; 2013; 98(2); 279-87; 22929983

Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and

van de Loosdrecht AA, Ireland R, Kern W, Della Porta MG, Alhan C, Balleisen JS, Bettelheim P, Bowen DT, Burbury K, Eidenschink L, Cazzola M, Chu SS, Cullen M, Cutler JA, Dräger AM, Feuillard J, Fenaux P, Font P, Germing U, Haase D, Hellström-Lindberg E, Johansson U, Kordasti S, Loken MR, Malcovati L, Te Marvelde JG, Matarraz S, Milne T, Moshaver B, Mufti GJ, Nikolova V, Ogata K, Oelschlaegel U, Orfao A, Ossenkoppele GJ, Porwit A, Platzbecker U, Preijers F, Psarra K, Richards SJ, Subira D, Seymour JF, Tindell V, Vallespi T, Valent P, van der Velden VH, Wells DA, de Witte TM, Zettl F, Béné MC, Westers TM, 
Leuk. Lymphoma; 2013; 54(3); 472-5; 22916713

Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry.

Pessoa de Magalhães RJ, Vidriales MB, Paiva B, Fernandez-Gimenez C, García-Sanz R, Mateos MV, Gutiérrez NC, Lecrevisse Q, Blanco JF, Hernandez J, de Las Heras N, Martinez-Lopez J, Roig M, Costa ES, Ocio EM, Pérez-Andrés M, Maiolino A, Nucci M, de la Rubia J, Lahuerta JJ, San-Miguel JF, Orfao A, , 
Haematologica; 2013; 98(1); 79-86; 22773604

Association of myelodysplastic syndrome with CD5+, CD23+ monoclonal B-cell lymphocytosis.

Sandes AF, Chauffaille Mde L, Orfao A, Siufi GC, Silva MR, Yamamoto M, 
Clinics (Sao Paulo); 2012; 67(12); 1487-91; 23295606

Common infectious agents and monoclonal B-cell lymphocytosis: a cross-sectional epidemiological study among healthy adults.

Casabonne D, Almeida J, Nieto WG, Romero A, Fernández-Navarro P, Rodríguez-Caballero A, Muñoz-Criado S, Díaz MG, Benavente Y, de Sanjosé S, Orfao A, , 
PLoS ONE; 2012; 7(12); e52808; 23285188

European Competence Network on Mastocytosis (ECNM): 10-year jubilee, update, and future perspectives.

Valent P, Arock M, Bonadonna P, Brockow K, Broesby-Olsen S, Escribano L, Gleixner KV, Grattan C, Hadzijusufovic E, Hägglund H, Hermine O, Horny HP, Kluin-Nelemans HC, Maurer M, Niedoszytko M, Nedoszytko B, Nilsson G, Oude-Elberink HN, Orfao A, Radia D, Reiter A, Siebenhaar F, Sotlar K, Sperr WR, Triggiani M, VanDoormaal JJ, Várkonyi J, Yavuz S, Hartmann K, 
Wien. Klin. Wochenschr.; 2012; 124(23-24); 807-14; 23179435

Self-assembled protein arrays from an Ornithodoros moubata salivary gland expression library.

Manzano-Román R, Díaz-Martín V, González-González M, Matarraz S, Álvarez-Prado AF, LaBaer J, Orfao A, Pérez-Sánchez R, Fuentes M, 
J. Proteome Res.; 2012; 11(12); 5972-82; 23140423

Amplified and homozygously deleted genes in glioblastoma: impact on gene expression levels.

Crespo I, Tão H, Nieto AB, Rebelo O, Domingues P, Vital AL, Patino Mdel C, Barbosa M, Lopes MC, Oliveira CR, Orfao A, Tabernero MD, 
PLoS ONE; 2012; 7(9); e46088; 23029397

Immunophenotypic identification and characterization of tumor cells and infiltrating cell populations in meningiomas.

Domingues PH, Teodosio C, Ortiz J, Sousa P, Otero A, Maíllo A, Bárcena P, Garcia-Macias MC, Lopes MC, de Oliveira C, Orfao A, Tabernero MD, 
Am. J. Pathol.; 2012; 181(5); 1749-61; 22982440

Multiparameter flow cytometry evaluation of plasma cell DNA content and proliferation in 595 transplant-eligible patients with myeloma included in the

Paiva B, Vidriales MB, Montalbán MA, Perez JJ, Gutiérrez NC, Rosiñol L, Martinez-Lopez J, Mateos MV, Cordón L, Oriol A, Terol MJ, Echeveste MA, de Paz R, de Arriba F, Palomera L, de la Rubia J, Díaz-Mediavilla J, Sureda A, Gorosquieta A, Alegre A, Martín A, Lahuerta JJ, Bladé J, Orfao A, San Miguel JF, 
Am. J. Pathol.; 2012; 181(5); 1870-8; 22974582

Extensive blistering is a predictor for severe complications in children with mastocytosis.

Brockow K, Ring J, Alvarez-Twose I, Orfao A, Escribano L, 
Allergy; 2012; 67(10); 1323-4; 22971120

Enhanced immunological response by dendritic cells in male hypogonadism.

Corrales JJ, Almeida M, Cordero M, Martín-Martín L, Méndez C, Miralles JM, Orfao A, 
Eur. J. Clin. Invest.; 2012; 42(11); 1205-12; 22957648

The proliferation index of specific bone marrow cell compartments from myelodysplastic syndromes is associated with the diagnostic and patient outcome

Matarraz S, Teodosio C, Fernández C, Albors M, Jara-Acevedo M, López A, González-González M, Gutiérrez ML, Flores-Montero J, Cerveró C, Pizarro-Perea M, Paz Garrastazul M, Caballero G, Gutiérrez O, Mendez GD, González-Silva M, Laranjeira P, Orfao A, 
PLoS ONE; 2012; 7(8); e44321; 22952954

EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols.

Kalina T, Flores-Montero J, van der Velden VH, Martín-Ayuso M, Böttcher S, Ritgen M, Almeida J, Lhermitte L, Asnafi V, Mendonça A, de Tute R, Cullen M, Sedek L, Vidriales MB, Perez JJ, Te Marvelde JG, Mejstríková E, Hrusak O, Szczepański T, van Dongen JJ, Orfao A, , 
Leukemia; 2012; 26(9); 1986-201; 22948490

Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia.

Dekking EH, van der Velden VH, Varro R, Wai H, Böttcher S, Kneba M, Sonneveld E, Koning A, Boeckx N, Van Poecke N, Lucio P, Mendonça A, Sedek L, Szczepański T, Kalina T, Kanderová V, Hoogeveen P, Flores-Montero J, Chillón MC, Orfao A, Almeida J, Evans P, Cullen M, Noordijk AL, Vermeulen PM, de Man MT, Dixon EP, Comans-Bitter WM, van Dongen JJ, , 
Leukemia; 2012; 26(9); 1976-85; 22948489

EuroFlow: Resetting leukemia and lymphoma immunophenotyping. Basis for companion diagnostics and personalized medicine.

van Dongen JJ, Orfao A, , 
Leukemia; 2012; 26(9); 1899-907; 22948488

Prognostic Impact of del(17p) and del(22q) as assessed by interphase FISH in sporadic colorectal carcinomas.

González-González M, Muñoz-Bellvis L, Mackintosh C, Fontanillo C, Gutiérrez ML, Abad MM, Bengoechea O, Teodosio C, Fonseca E, Fuentes M, De Las Rivas J, Orfao A, Sayagués JM, 
PLoS ONE; 2012; 7(8); e42683; 22912721

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.

Vicente-Dueñas C, Romero-Camarero I, González-Herrero I, Alonso-Escudero E, Abollo-Jiménez F, Jiang X, Gutiérrez NC, Orfao A, Marín N, Villar LM, Criado MC, Pintado B, Flores T, Alonso-López D, De Las Rivas J, Jiménez R, Criado FJ, Cenador MB, Lossos IS, Cobaleda C, Sánchez-García I, 
EMBO J.; 2012; 31(18); 3704-17; 22903061

Contribution of highly sensitive diagnostic methods to the diagnosis of systemic mastocytosis in the absence of skin lesions.

Alvarez-Twose I, Matito A, Sánchez-Muñoz L, Morgado JM, Orfao A, Escribano L, van Doormaal JJ, van der Veer E, van Voorst Vader PC, Kluin PM, Mulder AB, van der Heide S, Arends S, Kluin-Nelemans JC, Oude Elberink JN, de Monchy JG, 
Allergy; 2012; 67(9); 1190-1; 22882359

Evaluation of chemically modified carrier proteins for developing monoclonal antibodies against a clinically relevant mutation of cKIT.

Jara-Acevedo R, González-González M, Jara-Acevedo M, Claros J, Conde A, López-Pérez R, Orfao A, Fuentes M, 
J. Immunol. Methods; 2012; 384(1-2); 171-6; 22835433

Mast cell-related disorders presenting with Kounis syndrome.

González-de-Olano D, Matito A, Sánchez-López P, Sánchez-Muñoz L, Morgado JM, Teodosio C, Jara-Acevedo M, García-Montero A, Orfao A, Escribano L, Kounis NG, Alvarez-Twose I, 
Int. J. Cardiol.; 2012; 161(1); 56-8; 22748285

Monoclonal B-cell lymphocytosis (MBL) with normal lymphocyte counts is associated with decreased numbers of normal circulating B-cell subsets.

Hauswirth AW, Almeida J, Nieto WG, Teodosio C, Rodríguez-Caballero A, Romero A, López A, Fernández-Navarro P, Vega T, Pérez-Andrés M, Valent P, Jäger U, Orfao A, , 
Am. J. Hematol.; 2012; 87(7); 721-4; 22685020

EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes.

van Dongen JJ, Lhermitte L, Böttcher S, Almeida J, van der Velden VH, Flores-Montero J, Rawstron A, Asnafi V, Lecrevisse Q, Lucio P, Mejstríková E, Szczepański T, Kalina T, de Tute R, Brüggemann M, Sedek L, Cullen M, Langerak AW, Mendonça A, Macintyre E, Martín-Ayuso M, Hrusak O, Vidriales MB, Orfao A, , 
Leukemia; 2012; 26(9); 1908-75; 22552007

Current state of biology and diagnosis of clonal mast cell diseases in adults.

Alvarez-Twose I, Morgado JM, Sánchez-Muñoz L, García-Montero A, Mollejo M, Orfao A, Escribano L, 
Int J Lab Hematol; 2012; 34(5); 445-60; 22551157

Myelodysplasia-associated immunophenotypic alterations of bone marrow cells in myeloma: are they present at diagnosis or are they induced by lenalidom

, Matarraz S, Paiva B, Diez-Campelo M, López-Corral L, Pérez E, Mateos MV, Giraldo P, Hernández MT, San Miguel JF, Orfao A, 
Haematologica; 2012; 97(10); 1608-11; 22511492

Increased serum baseline tryptase levels and extensive skin involvement are predictors for the severity of mast cell activation episodes in children w

Alvarez-Twose I, Vañó-Galván S, Sánchez-Muñoz L, Morgado JM, Matito A, Torrelo A, Jaén P, Schwartz LB, Orfao A, Escribano L, 
Allergy; 2012; 67(6); 813-21; 22458675

Bone marrow transplantation extends its scope.

Sanchez-Guijo FM, Orfao A, del Cañizo MC, 
Adv. Exp. Med. Biol.; 2012; 741(); 121-34; 22457107

Biomarker discovery by novel sensors based on nanoproteomics approaches.

Dasilva N, Díez P, Matarraz S, González-González M, Paradinas S, Orfao A, Fuentes M, 
Sensors (Basel); 2012; 12(2); 2284-308; 22438764

Delineation of commonly deleted chromosomal regions in meningiomas by high-density single nucleotide polymorphism genotyping arrays.

Tabernero MD, Maíllo A, Nieto AB, Diez-Tascón C, Lara M, Sousa P, Otero A, Castrillo A, Patino-Alonso Mdel C, Espinosa A, Mackintosh C, de Alava E, Orfao A, 
Genes Chromosomes Cancer; 2012; 51(6); 606-17; 22371336

Complete response after imatinib mesylate therapy in a patient with well-differentiated systemic mastocytosis.

Alvarez-Twose I, González P, Morgado JM, Jara-Acevedo M, Sánchez-Muñoz L, Matito A, Mollejo M, Orfao A, Escribano L, 
J. Clin. Oncol.; 2012; 30(12); e126-9; 22370312

Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients.

Paiva B, Gutiérrez NC, Chen X, Vidriales MB, Montalbán MA, Rosiñol L, Oriol A, Martinez-Lopez J, Mateos MV, López-Corral L, Díaz-Rodríguez E, Perez JJ, Fernandez-Redondo E, de Arriba F, Palomera L, Bengoechea E, Terol MJ, de Paz R, Martín A, Hernandez J, Orfao A, Lahuerta JJ, Bladé J, Pandiella A, Miguel JF, , 
Leukemia; 2012; 26(8); 1862-9; 22333880

CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype.

Paíno T, Ocio EM, Paiva B, San-Segundo L, Garayoa M, Gutiérrez NC, Sarasquete ME, Pandiella A, Orfao A, San Miguel JF, 
Haematologica; 2012; 97(7); 1110-4; 22315496

Standardization of flow cytometry in myelodysplastic syndromes: a report from an international consortium and the European LeukemiaNet Working Group.

Westers TM, Ireland R, Kern W, Alhan C, Balleisen JS, Bettelheim P, Burbury K, Cullen M, Cutler JA, Della Porta MG, Dräger AM, Feuillard J, Font P, Germing U, Haase D, Johansson U, Kordasti S, Loken MR, Malcovati L, Te Marvelde JG, Matarraz S, Milne T, Moshaver B, Mufti GJ, Ogata K, Orfao A, Porwit A, Psarra K, Richards SJ, Subira D, Tindell V, Vallespi T, Valent P, van der Velden VH, de Witte TM, Wells DA, Zettl F, Béné MC, van de Loosdrecht AA, 
Leukemia; 2012; 26(7); 1730-41; 22307178

Altered immunophenotypic features of peripheral blood platelets in myelodysplastic syndromes.

Sandes AF, Yamamoto M, Matarraz S, Chauffaille Mde L, Quijano S, López A, Oguro T, Kimura EY, Orfao A, 
Haematologica; 2012; 97(6); 895-902; 22271903

Unique genetic profile of sporadic colorectal cancer liver metastasis versus primary tumors as defined by high-density single-nucleotide polymorphism

Muñoz-Bellvis L, Fontanillo C, González-González M, Garcia E, Iglesias M, Esteban C, Gutiérrez ML, Abad MM, Bengoechea O, De Las Rivas J, Orfao A, Sayagués JM, 
Mod. Pathol.; 2012; 25(4); 590-601; 22222638

Platinum complexes for multi-parametric assays using microarray systems.

González M, Bartolomé R, Matarraz S, Rodríguez-Fernández E, Manzano JL, Pérez-Andrés M, Orfao A, Fuentes M, Criado JJ, 
J. Inorg. Biochem.; 2012; 106(1); 43-5; 22112838

An immature immunophenotype of bone marrow mast cells predicts for multilineage D816V KIT mutation in systemic mastocytosis.

Teodosio C, García-Montero AC, Jara-Acevedo M, Alvarez-Twose I, Sánchez-Muñoz L, Almeida J, Morgado JM, Matito A, Escribano L, Orfao A, 
Leukemia; 2012; 26(5); 951-8; 22051531

Validation of the REMA score for predicting mast cell clonality and systemic mastocytosis in patients with systemic mast cell activation symptoms.

Alvarez-Twose I, González-de-Olano D, Sánchez-Muñoz L, Matito A, Jara-Acevedo M, Teodosio C, García-Montero A, Morgado JM, Orfao A, Escribano L, 
Int. Arch. Allergy Immuno; 2012; 157(3); 275-80; 22042301

Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal.

Valent P, Akin C, Arock M, Brockow K, Butterfield JH, Carter MC, Castells M, Escribano L, Hartmann K, Lieberman P, Nedoszytko B, Orfao A, Schwartz LB, Sotlar K, Sperr WR, Triggiani M, Valenta R, Horny HP, Metcalfe DD, 
Int. Arch. Allergy Immuno; 2012; 157(3); 215-25; 22041891

Nanotechniques in proteomics: protein microarrays and novel detection platforms.

González-González M, Jara-Acevedo R, Matarraz S, Jara-Acevedo M, Paradinas S, Sayagués JM, Orfao A, Fuentes M, 
Eur J Pharm Sci; 2012; 45(4); 499-506; 21803154

The nature of circulating CD27+CD43+ B cells.

Pérez-Andrés M, Grosserichter-Wagener C, Teodosio C, van Dongen JJ, Orfao A, Van Zelm MC, 
J. Exp. Med.; 2011; 208(13); 2565-6; 22184681

Multiparametric flow cytometry for identification and fluorescence activated cell sorting of five distinct B-cell subpopulations in normal tonsil tiss

Kjeldsen MK, Pérez-Andrés M, Schmitz A, Johansen P, Boegsted M, Nyegaard M, Gaihede M, Bukh A, Johnsen HE, Orfao A, Dybkaer K, 
Am. J. Clin. Pathol.; 2011; 136(6); 960-9; 22095383

Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymor

Diamond HR, Ornellas MH, Orfao A, Gomes BE, Campos MM, Fernandez TS, da Silva RI, Alves G, Lage C, da Silva DA, Moellmann-Coelho A, da Cruz GS, Bouzas LF, Abdelhay E, 
J Hematol Oncol; 2011; 4(); 39; 21951951

Detailed characterization of alterations of chromosomes 7, 9, and 10 in glioblastomas as assessed by single-nucleotide polymorphism arrays.

Crespo I, Vital AL, Nieto AB, Rebelo O, Tão H, Lopes MC, Oliveira CR, French PJ, Orfao A, Tabernero MD, 
J Mol Diagn; 2011; 13(6); 634-47; 21884817

Dermoscopic features of skin lesions in patients with mastocytosis.

Vano-Galvan S, Alvarez-Twose I, De las Heras E, Heras Ede L, Morgado JM, Matito A, Sánchez-Muñoz L, Plana MN, Planas MN, Jaén P, Orfao A, Escribano L, 
Arch Dermatol; 2011; 147(8); 932-40; 21844452

Association between genetic subgroups of pancreatic ductal adenocarcinoma defined by high density 500 K SNP-arrays and tumor histopathology.

Gutiérrez ML, Muñoz-Bellvis L, Abad Mdel M, Bengoechea O, González-González M, Orfao A, Sayagués JM, 
PLoS ONE; 2011; 6(7); e22315; 21811587

Heme-oxygenases during erythropoiesis in K562 and human bone marrow cells.

Alves LR, Costa ES, Sorgine MH, Nascimento-Silva MC, Teodosio C, Bárcena P, Castro-Faria-Neto HC, Bozza PT, Orfao A, Oliveira PL, Maya-Monteiro CM, 
PLoS ONE; 2011; 6(7); e21358; 21765894

Cell-cycle distribution of different cell compartments in normal versus reactive bone marrow: a frame of reference for the study of dysplastic hematop

Matarraz S, Fernández C, Albors M, Teodosio C, López A, Jara-Acevedo M, Cerveró C, Caballero G, Gutiérrez O, Orfao A, 
Cytometry B Clin Cytom; 2011; 80(6); 354-61; 21638773

Venom immunotherapy in patients with mastocytosis and hymenoptera venom anaphylaxis.

González-de-Olano D, Alvarez-Twose I, Vega A, Orfao A, Escribano L, 
Immunotherapy; 2011; 3(5); 637-51; 21554093

Evaluation of the WHO criteria for the classification of patients with mastocytosis.

Sánchez-Muñoz L, Alvarez-Twose I, García-Montero AC, Teodosio C, Jara-Acevedo M, Pedreira CE, Matito A, Morgado JM, Sanchez ML, Mollejo M, González-de-Olano D, Orfao A, Escribano L, 
Mod. Pathol.; 2011; 24(9); 1157-68; 21552214

Evaluation of basophil activation in mastocytosis with Hymenoptera venom anaphylaxis.

González-de-Olano D, Alvarez-Twose I, Morgado JM, Esteban López MI, Vega Castro A, Díaz de Durana MD, Sánchez-Muñoz L, Matito A, de la Hoz Caballer B, Sanz ML, Orfao A, Escribano L, 
Cytometry B Clin Cytom; 2011; 80(3); 167-75; 21520404

Indolent systemic mastocytosis without skin involvement vs. isolated bone marrow mastocytosis.

Escribano L, Alvarez-Twose I, García-Montero A, Sánchez-Muñoz L, Jara-Acevedo M, Orfao A, 
Haematologica; 2011; 96(4); e26; aut; 21454873

Clinical impact of pregnancy in mastocytosis: a study of the Spanish Network on Mastocytosis (REMA) in 45 cases.

Matito A, Alvarez-Twose I, Morgado JM, Sánchez-Muñoz L, Orfao A, Escribano L, 
Int. Arch. Allergy Immuno; 2011; 156(1); 104-11; 21447966

Flow cytometry immunophenotyping of fine-needle aspiration specimens: utility in the diagnosis and classification of non-Hodgkin lymphomas.

Barrena S, Almeida J, del Carmen García-Macias M, López A, Rasillo A, Sayagués JM, Rivas RA, Gutiérrez ML, Ciudad J, Flores T, Balanzategui A, Caballero MD, Orfao A, 
Histopathology; 2011; 58(6); 906-18; 21438908

New technologies in cancer. Protein microarrays for biomarker discovery.

Matarraz S, González-González M, Jara M, Orfao A, Fuentes M, 
Clin Transl Oncol; 2011; 13(3); 156-61; 21421460

Comparison of immunofixation, serum free light chain, and immunophenotyping for response evaluation and prognostication in multiple myeloma.

Paiva B, Martinez-Lopez J, Vidriales MB, Mateos MV, Montalbán MA, Fernandez-Redondo E, Alonso L, Oriol A, Teruel AI, de Paz R, Laraña JG, Bengoechea E, Martín A, Mediavilla JD, Palomera L, de Arriba F, Bladé J, Orfao A, Lahuerta JJ, San Miguel JF, 
J. Clin. Oncol.; 2011; 29(12); 1627-33; 21402611

Cytogenetic heterogeneity of pancreatic ductal adenocarcinomas: identification of intratumoral pathways of clonal evolution.

Gutiérrez ML, Sayagués JM, Abad Mdel M, Bengoechea O, González-González M, Orfao A, Muñoz-Bellvis L, 
Histopathology; 2011; 58(3); 486-97; 21323969

Competition between clonal plasma cells and normal cells for potentially overlapping bone marrow niches is associated with a progressively altered cel

Paiva B, Pérez-Andrés M, Vidriales MB, Almeida J, de Las Heras N, Mateos MV, López-Corral L, Gutiérrez NC, Blanco J, Oriol A, Hernández MT, de Arriba F, de Coca AG, Terol MJ, de la Rubia J, González Y, Martín A, Sureda A, Schmidt-Hieber M, Schmitz A, Johnsen HE, Lahuerta JJ, Bladé J, San-Miguel JF, Orfao A, , 
Leukemia; 2011; 25(4); 697-706; 21252988

Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10.

Béné MC, Nebe T, Bettelheim P, Buldini B, Bumbea H, Kern W, Lacombe F, Lemez P, Marinov I, Matutes E, Maynadié M, Oelschlagel U, Orfao A, Schabath R, Solenthaler M, Tschurtschenthaler G, Vladareanu AM, Zini G, Faure GC, Porwit A, 
Leukemia; 2011; 25(4); 567-74; 21252983

CLL-like B-lymphocytes are systematically present at very low numbers in peripheral blood of healthy adults.

Almeida J, Nieto WG, Teodosio C, Pedreira CE, López A, Fernández-Navarro P, Nieto A, Rodríguez-Caballero A, Muñoz-Criado S, Jara-Acevedo M, Romero A, Orfao A, , 
Leukemia; 2011; 25(4); 718-22; 21233839

Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification.

Matutes E, Pickl WF, Van't Veer M, Morilla R, Swansbury J, Strobl H, Attarbaschi A, Hopfinger G, Ashley S, Béné MC, Porwit A, Orfao A, Lemez P, Schabath R, Ludwig WD, 
Blood; 2011; 117(11); 3163-71; 21228332

[Diagnosis and treatment of nocturnal paroxysmal hemoglobinuria].

Urbano-Ispizua A, Gaya A, Colado E, López M, Arrizabalaga B, Vicente V, Orfao A, Villegas A, Vallejo C, 
Med Clin (Barc); 2011; 136(3); 121-7; 21075403

Mobilization of plasma cells in healthy individuals treated with granulocyte colony-stimulating factor for haematopoietic stem cell collection.

Caraux A, Pérez-Andrés M, Larroque M, Requirand G, Lu ZY, Kanouni T, Rossi JF, Orfao A, Klein B, 
Immunology; 2011; 132(2); 266-72; 21039470

CD117 expression in gammopathies is associated with an altered maturation of the myeloid and lymphoid hematopoietic cell compartments and favorable di

Schmidt-Hieber M, Pérez-Andrés M, Paiva B, Flores-Montero J, Perez JJ, Gutiérrez NC, Vidriales MB, Matarraz S, San Miguel JF, Orfao A, 
Haematologica; 2011; 96(2); 328-32; 20971816

Detection of fusion genes at the protein level in leukemia patients via the flow cytometric immunobead assay.

Dekking E, van der Velden VH, Böttcher S, Brüggemann M, Sonneveld E, Koning-Goedheer A, Boeckx N, Lucio P, Sedek L, Szczepański T, Kalina T, Kovac M, Evans P, Hoogeveen PG, Flores-Montero J, Orfao A, Comans-Bitter WM, Staal FJ, van Dongen JJ, , 
Best Pract Res Clin Haema; 2010; 23(3); 333-45; 21123134

Mapping of genetic abnormalities of primary tumours from metastatic CRC by high-resolution SNP arrays.

Sayagués JM, Fontanillo C, Abad Mdel M, González-González M, Sarasquete ME, Chillon Mdel C, Garcia E, Bengoechea O, Fonseca E, Gonzalez-Diaz M, De Las Rivas J, Muñoz-Bellvis L, Orfao A, 
PLoS ONE; 2010; 5(10); e13752; 21060790

Automated pattern-guided principal component analysis vs expert-based immunophenotypic classification of B-cell chronic lymphoproliferative disorders:

Costa ES, Pedreira CE, Barrena S, Lecrevisse Q, Flores J, Quijano S, Almeida J, del Carmen García-Macias M, Böttcher S, van Dongen JJ, Orfao A, 
Leukemia; 2010; 24(11); 1927-33; 20844562

Human peripheral blood B-cell compartments: a crossroad in B-cell traffic.

Pérez-Andrés M, Paiva B, Nieto WG, Caraux A, Schmitz A, Almeida J, Vogt RF, Marti GE, Rawstron AC, Van Zelm MC, van Dongen JJ, Johnsen HE, Klein B, Orfao A, , 
Cytometry B Clin Cytom; 2010; 78 Suppl 1; S47-60; 20839338

Commentary: Comparison of current flow cytometry methods for monoclonal B cell lymphocytosis detection.

Nieto WG, Almeida J, Teodosio C, Abbasi F, Allgood SD, Connors F, Rachel JM, Ghia P, Lanasa MC, Rawstron AC, Orfao A, Caporaso NE, Hanson CA, Shim YK, Vogt RF, Marti GE, 
Cytometry B Clin Cytom; 2010; 78 Suppl 1; S4-9; 20839336

Non-CLL-like monoclonal B-cell lymphocytosis in the general population: prevalence and phenotypic/genetic characteristics.

Nieto WG, Teodosio C, López A, Rodríguez-Caballero A, Romero A, Bárcena P, Gutiérrez ML, Langerak AW, Fernández-Navarro P, Orfao A, Almeida J, , 
Cytometry B Clin Cytom; 2010; 78 Suppl 1; S24-34; 20839335

Different biology and clinical outcome according to the absolute numbers of clonal B-cells in monoclonal B-cell lymphocytosis (MBL).

Rawstron AC, Shanafelt T, Lanasa MC, Landgren O, Hanson C, Orfao A, Hillmen P, Ghia P, 
Cytometry B Clin Cytom; 2010; 78 Suppl 1; S19-23; 20839333

Prevalence of monoclonal B-cell lymphocytosis: a systematic review.

Shim YK, Middleton DC, Caporaso NE, Rachel JM, Landgren O, Abbasi F, Raveche ES, Rawstron AC, Orfao A, Marti GE, Vogt RF, 
Cytometry B Clin Cytom; 2010; 78 Suppl 1; S10-8; 20839330

Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases.

Lemez P, Attarbaschi A, Béné MC, Bertrand Y, Castoldi G, Forestier E, Garand R, Haas OA, Kagialis-Girard S, Ludwig WD, Matutes E, Mejstríková E, Pages MP, Pickl W, Porwit A, Orfao A, Schabath R, Starý J, Strobl H, Talmant P, Van't Veer MB, Zemanová Z, , 
Eur. J. Haematol.; 2010; 85(4); 300-8; 20561032

Intratumoural cytogenetic heterogeneity of sporadic colorectal carcinomas suggests several pathways to liver metastasis.

Sayagués JM, Abad Mdel M, Melchor HB, Gutiérrez ML, González-González M, Jensen E, Bengoechea O, Fonseca E, Orfao A, Muñoz-Bellvis L, 
J. Pathol.; 2010; 221(3); 308-19; 20527024

Gene expression profiles of human glioblastomas are associated with both tumor cytogenetics and histopathology.

Vital AL, Tabernero MD, Castrillo A, Rebelo O, Tão H, Gomes F, Nieto AB, Resende Oliveira C, Lopes MC, Orfao A, 
Neuro-oncology; 2010; 12(9); 991-1003; 20484145

Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms.

Alvarez-Twose I, González de Olano D, Sánchez-Muñoz L, Matito A, Esteban-López MI, Vega A, Mateo MB, Alonso Díaz de Durana MD, de la Hoz B, Del Pozo Gil MD, Caballero T, Rosado A, Sánchez Matas I, Teodosio C, Jara-Acevedo M, Mollejo M, García-Montero A, Orfao A, Escribano L, 
J. Allergy Clin. Immunol.; 2010; 125(6); 1269-127; 20434205

Bcl2 is not required for the development and maintenance of leukemia stem cells in mice.

González-Herrero I, Vicente-Dueñas C, Orfao A, Flores T, Jiménez R, Cobaleda C, Sánchez-García I, 
Carcinogenesis; 2010; 31(7); 1292-7; 20299524

Chronic alcohol consumption is associated with an increased cytotoxic profile of circulating lymphocytes that may be related with the development of l

Laso FJ, Almeida J, Torres E, Vaquero JM, Marcos M, Orfao A, 
Alcohol. Clin. Exp. Res.; 2010; 34(5); 876-85; 20201930

Bone marrow cells from myelodysplastic syndromes show altered immunophenotypic profiles that may contribute to the diagnosis and prognostic stratifica

Matarraz S, López A, Barrena S, Fernández C, Jensen E, Flores-Montero J, Rasillo A, Sayagués JM, Sanchez ML, Bárcena P, Hernandez-Rivas JM, Salvador C, Fernández-Mosteirín N, Giralt M, Perdiguer L, Laranjeira P, Paiva A, Orfao A, 
Cytometry B Clin Cytom; 2010; 78(3); 154-68; 20198685

Utility of flow cytometry immunophenotyping in multiple myeloma and other clonal plasma cell-related disorders.

Paiva B, Almeida J, Pérez-Andrés M, Mateo G, López A, Rasillo A, Vidriales MB, López-Berges MC, Miguel JF, Orfao A, 
Cytometry B Clin Cytom; 2010; 78(4); 239-52; 20155853

Circulating human B and plasma cells. Age-associated changes in counts and detailed characterization of circulating normal CD138- and CD138+ plasma ce

Caraux A, Klein B, Paiva B, Bret C, Schmitz A, Fuhler GM, Bos NA, Johnsen HE, Orfao A, Pérez-Andrés M, , 
Haematologica; 2010; 95(6); 1016-20; 20081059

Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes.

Teodosio C, García-Montero AC, Jara-Acevedo M, Sánchez-Muñoz L, Alvarez-Twose I, Núñez R, Schwartz LB, Walls AF, Escribano L, Orfao A, 
J. Allergy Clin. Immunol.; 2010; 125(3); 719-26, ; 20061010

The Wnt signaling pathway regulates Nalm-16 b-cell precursor acute lymphoblastic leukemic cell line survival and etoposide resistance.

Thiago LS, Costa ES, Lopes DV, Otazu IB, Nowill AE, Mendes FA, Portilho DM, Abreu JG, Mermelstein CS, Orfao A, Rossi MI, Borojevic R, 
Biomed. Pharmacother.; 2010; 64(1); 63-72; 19864107

Risk of progression in smouldering myeloma and monoclonal gammopathies of unknown significance: comparative analysis of the evolution of monoclonal co

Pérez-Persona E, Mateo G, García-Sanz R, Mateos MV, de Las Heras N, de Coca AG, Hernández JM, Galende J, Martín-Nuñez G, Bárez A, Alonso JM, Martín A, López-Berges C, Orfao A, San Miguel JF, Vidriales MB, 
Br. J. Haematol.; 2010; 148(1); 110-4; 19821821

Intratumoral patterns of clonal evolution in gliomas.

Vital AL, Tabernero MD, Crespo I, Rebelo O, Tão H, Gomes F, Lopes MC, Orfao A, 
Neurogenetics; 2010; 11(2); 227-39; 19760258

Harmonization of light scatter and fluorescence flow cytometry profiles obtained after staining peripheral blood leucocytes for cell surface-only vers

da Costa ES, Peres RT, Almeida J, Lecrevisse Q, Arroyo ME, Teodosio C, Pedreira CE, van Dongen JJ, Orfao A, , 
Cytometry B Clin Cytom; 2010; 78(1); 11-20; 19575389

Multiparameter flow cytometry quantification of bone marrow plasma cells at diagnosis provides more prognostic information than morphological assessme

Paiva B, Vidriales MB, Perez JJ, Mateo G, Montalbán MA, Mateos MV, Bladé J, Lahuerta JJ, Orfao A, San Miguel JF, , 
Haematologica; 2009; 94(11); 1599-602; 19880781

The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic mul

Paiva B, Vidriales MB, Mateo G, Perez JJ, Montalbán MA, Sureda A, Montejano L, Gutiérrez NC, García de Coca A, de Las Heras N, Mateos MV, López-Berges MC, García-Boyero R, Galende J, Hernandez J, Palomera L, Carrera D, Martínez R, de la Rubia J, Martín A, González Y, Bladé J, Lahuerta JJ, Orfao A, San-Miguel JF, , 
Blood; 2009; 114(20); 4369-72; 19755674

Fluorescent cisplatin analogues and cytotoxic activity.

Rodríguez-Fernández E, Manzano JL, Alonso A, Almendral MJ, Pérez-Andrés M, Orfao A, Criado JJ, 
Curr. Med. Chem.; 2009; 16(32); 4314-27; 19754416

Standardization of flow cytometry in myelodysplastic syndromes: report from the first European LeukemiaNet working conference on flow cytometry in mye

van de Loosdrecht AA, Alhan C, Béné MC, Della Porta MG, Dräger AM, Feuillard J, Font P, Germing U, Haase D, Homburg CH, Ireland R, Jansen JH, Kern W, Malcovati L, Te Marvelde JG, Mufti GJ, Ogata K, Orfao A, Ossenkoppele GJ, Porwit A, Preijers FW, Richards SJ, Schuurhuis GJ, Subira D, Valent P, van der Velden VH, Vyas P, Westra AH, de Witte TM, Wells DA, Loken MR, Westers TM, 
Haematologica; 2009; 94(8); 1124-34; 19546437

Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients.

Escribano L, Alvarez-Twose I, Sánchez-Muñoz L, García-Montero A, Núñez R, Almeida J, Jara-Acevedo M, Teodosio C, García-Cosío M, Bellas C, Orfao A, 
J. Allergy Clin. Immunol.; 2009; 124(3); 514-21; 19541349

Increased frequency (12%) of circulating chronic lymphocytic leukemia-like B-cell clones in healthy subjects using a highly sensitive multicolor flow

Nieto WG, Almeida J, Romero A, Teodosio C, López A, Henriques AF, Sanchez ML, Jara-Acevedo M, Rasillo A, González M, Fernández-Navarro P, Vega T, Orfao A, , 
Blood; 2009; 114(1); 33-7; 19420353

Immunophenotypical, morphologic, and functional characterization of maturation-associated plasmacytoid dendritic cell subsets in normal adult human bo

Martín-Martín L, Almeida J, Hernández-Campo PM, Sanchez ML, Lecrevisse Q, Orfao A, 
Transfusion; 2009; 49(8); 1692-170; 19392773

Flow cytometric immunobead assay for the detection of BCR-ABL fusion proteins in leukemia patients.

Weerkamp F, Dekking E, Ng YY, van der Velden VH, Wai H, Böttcher S, Brüggemann M, van der Sluijs AJ, Koning A, Boeckx N, Van Poecke N, Lucio P, Mendonça A, Sedek L, Szczepański T, Kalina T, Kovac M, Hoogeveen PG, Flores-Montero J, Orfao A, Macintyre E, Lhermitte L, Chen R, Brouwer-De Cock KA, van der Linden A, Noordijk AL, Comans-Bitter WM, Staal FJ, van Dongen JJ, , 
Leukemia; 2009; 23(6); 1106-17; 19387467

Prolonged idiotypic vaccination against follicular lymphoma.

Inogés S, López-Díaz de Cerio A, Zabalegui N, Soria E, Villanueva H, Panizo C, Rodríguez-Caballero A, Suárez L, Pastor F, Rodríguez-Calvillo M, Orfao A, Bendandi M, 
Leuk. Lymphoma; 2009; 50(1); 47-53; 19152172

Cancer induction by restriction of oncogene expression to the stem cell compartment.

Pérez-Caro M, Cobaleda C, González-Herrero I, Vicente-Dueñas C, Bermejo-Rodríguez C, Sánchez-Beato M, Orfao A, Pintado B, Flores T, Sánchez-Martín M, Jiménez R, Piris MA, Sánchez-García I, 
EMBO J.; 2009; 28(1); 8-20; 19037256

Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple my

Pérez-Andrés M, Almeida J, Martín-Ayuso M, de Las Heras N, Moro MJ, Martín-Nuñez G, Galende J, Cuello R, Abuín I, Moreno I, Domínguez M, Hernandez J, Mateo G, San Miguel JF, Orfao A, 
Int. J. Cancer; 2009; 124(2); 367-75; 19003959

Genetic stability of human embryonic stem cells: A first-step toward the development of potential hESC-based systems for modeling childhood leukemia.

Catalina P, Bueno C, Montes R, Nieto A, Ligero G, Sanchez L, Jara M, Rasillo A, Orfao A, Cigudosa J, Hovatta O, Greaves M, Menendez P, 
Leuk. Res.; 2009; 33(7); 980-90; 18930318

Persistence of androgenic effects on the production of proinflammatory cytokines by circulating antigen-presenting cells after withdrawal of testoster

Corrales JJ, Almeida M, Miralles JM, Orfao A, 
Fertil. Steril.; 2009; 92(1); 311-9; 18710716

Gene expression profiles of meningiomas are associated with tumor cytogenetics and patient outcome.

Tabernero MD, Maíllo A, Gil-Bellosta CJ, Castrillo A, Sousa P, Merino M, Orfao A, 
Brain Pathol.; 2009; 19(3); 409-20; 18637901

Successful treatment with VAD of a myelodysplastic syndrome occurring during the course of a smoldering multiple myeloma.

Cortesão E, Espadana A, Laranjeiro P, Jara M, Orfao A, 
Leuk. Res.; 2009; 33(1); 195-7; 18511113

[Paroxysmal nocturnal hemoglobinuria].

Hernández-Campo PM, Almeida J, Orfao A, 
Med Clin (Barc); 2008; 131(16); 617-30; 19080854

Bisursodeoxycholate(ethylenediamine)platinum(II): a new autofluorescent compound. Cytotoxic activity and cell cycle analysis in ovarian and hematologi

Pérez-Andrés M, Benito JJ, Rodríguez-Fernández E, Corradetti B, Primo D, Manzano JL, Orfao A, Criado JJ, 
Dalton Trans; 2008; (44); 6159-64; 18985248

A probabilistic approach for the evaluation of minimal residual disease by multiparameter flow cytometry in leukemic B-cell chronic lymphoproliferativ

Pedreira CE, Costa ES, Almeida J, Fernández C, Quijano S, Flores J, Barrena S, Lecrevisse Q, van Dongen JJ, Orfao A, , 
Cytometry A; 2008; 73A(12); 1141-50; 18836994

Flow cytometric immunophenotyping of cerebrospinal fluid.

Kraan J, Gratama JW, Haioun C, Orfao A, Plonquet A, Porwit A, Quijano S, Stetler-Stevenson M, Subira D, Wilson W, 
Curr Protoc Cytom; 2008; Chapter 6(; Unit 6.2; 18770650

Expanded cells in monoclonal TCR-alphabeta+/CD4+/NKa+/CD8-/+dim T-LGL lymphocytosis recognize hCMV antigens.

Rodríguez-Caballero A, García-Montero AC, Bárcena P, Almeida J, Ruiz-Cabello F, Tabernero MD, Garrido P, Muñoz-Criado S, Sandberg Y, Langerak AW, González M, Balanzategui A, Orfao A, 
Blood; 2008; 112(12); 4609-16; 18768393

NG2 antigen is expressed in CD34+ HPCs and plasmacytoid dendritic cell precursors: is NG2 expression in leukemia dependent on the target cell where le

Bueno C, Montes R, Martín L, Prat I, Hernandez MC, Orfao A, Menendez P, 
Leukemia; 2008; 22(8); 1475-8; 18698324

Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transpl

Paiva B, Vidriales MB, Cerveró J, Mateo G, Perez JJ, Montalbán MA, Sureda A, Montejano L, Gutiérrez NC, García de Coca A, de Las Heras N, Mateos MV, López-Berges MC, García-Boyero R, Galende J, Hernandez J, Palomera L, Carrera D, Martínez R, de la Rubia J, Martín A, Bladé J, Lahuerta JJ, Orfao A, San Miguel JF, , 
Blood; 2008; 112(10); 4017-23; 18669875

Generation of flow cytometry data files with a potentially infinite number of dimensions.

Pedreira CE, Costa ES, Barrena S, Lecrevisse Q, Almeida J, van Dongen JJ, Orfao A, , 
Cytometry A; 2008; 73(9); 834-46; 18629843

Array-based comparative genomic hybridization of mapped BAC DNA clones to screen for chromosome 14 copy number abnormalities in meningiomas.

Espinosa AB, Mackintosh C, Maíllo A, Gutierrez L, Sousa P, Merino M, Ortiz J, de Alava E, Orfao A, Tabernero MD, 
Eur. J. Hum. Genet.; 2008; 16(12); 1450-8; 18628790

Prognostic value of immunophenotyping in multiple myeloma: a study by the PETHEMA/GEM cooperative study groups on patients uniformly treated with high

Mateo G, Montalbán MA, Vidriales MB, Lahuerta JJ, Mateos MV, Gutiérrez N, Rosiñol L, Montejano L, Bladé J, Martínez R, de la Rubia J, Díaz-Mediavilla J, Sureda A, Ribera JM, Ojanguren JM, de Arriba F, Palomera L, Terol MJ, Orfao A, San Miguel JF, , 
J. Clin. Oncol.; 2008; 26(16); 2737-44; 18443352

Detailed immunophenotypic characterization of different major and minor subsets of peripheral blood cells in patients with paroxysmal nocturnal hemogl

Hernández-Campo PM, Almeida J, Acevedo MJ, Sanchez ML, Alberca I, Vidriales B, Martínez E, Romero JR, Orfao A, 
Transfusion; 2008; 48(7); 1403-14; 18422849

Flow cytometric analysis of intestinal intraepithelial lymphocytes in the diagnosis of refractory celiac sprue.

Sanchez-Muñoz LB, Santón A, Cano A, López A, Almeida J, Orfao A, Escribano L, Roy G, 
Eur J Gastroenterol Hepat; 2008; 20(5); 478-87; 18403953

Evaluation of functional single nucleotide polymorphisms of different genes coding for the immunoregulatory molecules in patients with monoclonal larg

Garrido P, Almeida J, Romero JM, Cantón J, Sandberg Y, Bárcena P, Lima M, Langerak AW, Orfao A, Ruiz-Cabello F, 
Hum. Immunol.; 2008; 69(2); 101-7; 18361934

Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma.

Armellini A, Sarasquete ME, García-Sanz R, Chillón MC, Balanzategui A, Alcoceba M, Fuertes M, López R, Hernández JM, Fernández-Calvo J, Sierra M, Megido M, Orfao A, Gutiérrez NC, González M, San Miguel JF, 
Br. J. Haematol.; 2008; 141(2); 212-5; 18353163

The immunophenotype of different immature, myeloid and B-cell lineage-committed CD34+ hematopoietic cells allows discrimination between normal/reactiv

Matarraz S, López A, Barrena S, Fernández C, Jensen E, Flores J, Bárcena P, Rasillo A, Sayagués JM, Sanchez ML, Hernandez-Campo P, Hernandez Rivas JM, Salvador C, Fernández-Mosteirín N, Giralt M, Perdiguer L, Orfao A, 
Leukemia; 2008; 22(6); 1175-83; 18337765

Association between the proliferative rate of neoplastic B cells, their maturation stage, and underlying cytogenetic abnormalities in B-cell chronic l

Quijano S, López A, Rasillo A, Barrena S, Luz Sánchez M, Flores J, Fernández C, Sayagués JM, Osuna CS, Fernández N, González M, Giraldo P, Giralt M, Pérez MC, Martin-Antoran JM, Gutiérrez O, Perdiguer L, Díaz Mediavilla J, González Silva M, Asensio Del Rio A, Cerveró C, Guerra JL, Butrón R, García Mdel C, Almeida J, Orfao A, 
Blood; 2008; 111(10); 5130-41; 18337555

A multidimensional classification approach for the automated analysis of flow cytometry data.

Pedreira CE, Costa ES, Arroyo ME, Almeida J, Orfao A, 
IEEE Trans Biomed Eng; 2008; 55(3); 1155-62; 18334408

Acute myeloid dendritic cell leukaemia with specific cutaneous involvement: a diagnostic challenge.

Ferran M, Gallardo F, Ferrer AM, Salar A, Pérez-Vila E, Juanpere N, Salgado R, Espinet B, Orfao A, Florensa L, Pujol RM, 
Br. J. Dermatol.; 2008; 158(5); 1129-33; 18294313

Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders.

Rawstron AC, Orfao A, Beksac M, Bezdickova L, Brooimans RA, Bumbea H, Dalva K, Fuhler G, Gratama J, Hose D, Kovarova L, Lioznov M, Mateo G, Morilla R, Mylin AK, Omedé P, Pellat-Deceunynck C, Perez Andres M, Petrucci M, Ruggeri M, Rymkiewicz G, Schmitz A, Schreder M, Seynaeve C, Spacek M, de Tute RM, Van Valckenborgh E, Weston-Bell N, Owen RG, San Miguel JF, Sonneveld P, Johnsen HE, , 
Haematologica; 2008; 93(3); 431-8; 18268286

Peripheral blood dendritic cell subsets from patients with monoclonal gammopathies show an abnormal distribution and are functionally impaired.

Martín-Ayuso M, Almeida J, Pérez-Andrés M, Cuello R, Galende J, González-Fraile MI, Martín-Nuñez G, Ortega F, Rodríguez MJ, San Miguel JF, Orfao A, 
Oncologist; 2008; 13(1); 82-92; 18245015

Safety and effectiveness of immunotherapy in patients with indolent systemic mastocytosis presenting with Hymenoptera venom anaphylaxis.

González de Olano D, Alvarez-Twose I, Esteban-López MI, Sánchez-Muñoz L, de Durana MD, Vega A, García-Montero A, González-Mancebo E, Belver T, Herrero-Gil MD, Fernández-Rivas M, Orfao A, de la Hoz B, Castells MC, Escribano L, 
J. Allergy Clin. Immunol.; 2008; 121(2); 519-26; 18177694

Impact of trisomy 12, del(13q), del(17p), and del(11q) on the immunophenotype, DNA ploidy status, and proliferative rate of leukemic B-cells in chroni

Quijano S, López A, Rasillo A, Sayagués JM, Barrena S, Sanchez ML, Teodosio C, Giraldo P, Giralt M, Pérez MC, Romero M, Perdiguer L, Orfao A, 
Cytometry B Clin Cytom; 2008; 74(3); 139-49; 18061951

An uncommon case of childhood biphenotypic precursor-B/T acute lymphoblastic leukemia.

Costa ES, Thiago LS, Otazu IB, Ornellas MH, Land MG, Orfao A, 
Pediatr Blood Cancer; 2008; 50(4); 941-2; 17610263

Flow cytometry in myelodysplastic syndromes: report from a working conference.

Loken MR, van de Loosdrecht A, Ogata K, Orfao A, Wells DA, 
Leuk. Res.; 2008; 32(1); 5-17; 17576013

Molecular characterization of complete and incomplete immunoglobulin heavy chain gene rearrangements in hairy cell leukemia.

Martín-Jiménez P, García-Sanz R, González D, Balanzategui A, Perez JJ, Caballero MD, Sarasquete ME, Galende J, Orfao A, López-Berges MC, San Miguel JF, González M, 
Clin Lymphoma Myeloma; 2007; 7(9); 573-9; 18186965

Patient gender is associated with distinct patterns of chromosomal abnormalities and sex chromosome linked gene-expression profiles in meningiomas.

Tabernero MD, Espinosa AB, Maíllo A, Rebelo O, Vera JF, Sayagués JM, Merino M, Díaz P, Sousa P, Orfao A, 
Oncologist; 2007; 12(10); 1225-36; 17962616

(-)-Epigallocatechin-3-gallate interferes with mast cell adhesiveness, migration and its potential to recruit monocytes.

Melgarejo E, Medina MA, Sanchez-Jimenez F, Botana LM, Domínguez M, Escribano L, Orfao A, Urdiales JL, 
Cell. Mol. Life Sci.; 2007; 64(19-20); 2690-701; 17878996

2006 Bethesda International Consensus recommendations on the flow cytometric immunophenotypic analysis of hematolymphoid neoplasia: medical indication

Davis BH, Holden JT, Béné MC, Borowitz MJ, Braylan RC, Cornfield D, Gorczyca W, Lee R, Maiese R, Orfao A, Wells D, Wood BL, Stetler-Stevenson M, 
Cytometry B Clin Cytom; 2007; 72 Suppl 1; S5-13; 17803188

The Schistosoma bovis Sb14-3-3zeta recombinant protein cross-protects against Schistosoma mansoni in BALB/c mice.

Siles-Lucas M, Uribe N, López-Abán J, Vicente B, Orfao A, Nogal-Ruiz JJ, Feliciano AS, Muro A, 
Vaccine; 2007; 25(41); 7217-23; 17707955

Early recurrences in histologically benign/grade I meningiomas are associated with large tumors and coexistence of monosomy 14 and del(1p36) in the an

Maíllo A, Orfao A, Espinosa AB, Sayagués JM, Merino M, Sousa P, Lara M, Tabernero MD, 
Neuro-oncology; 2007; 9(4); 438-46; 17704362

New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparamete

Pérez-Persona E, Vidriales MB, Mateo G, García-Sanz R, Mateos MV, de Coca AG, Galende J, Martín-Nuñez G, Alonso JM, de Las Heras N, Hernández JM, Martín A, López-Berges C, Orfao A, San Miguel JF, 
Blood; 2007; 110(7); 2586-92; 17576818

Recent advances in the understanding of mastocytosis: the role of KIT mutations.

Orfao A, García-Montero AC, Sanchez L, Escribano L, , 
Br. J. Haematol.; 2007; 138(1); 12-30; 17555444

Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria.

Valent P, Akin C, Escribano L, Födinger M, Hartmann K, Brockow K, Castells M, Sperr WR, Kluin-Nelemans HC, Hamdy NA, Lortholary O, Robyn J, van Doormaal J, Sotlar K, Hauswirth AW, Arock M, Hermine O, Hellmann A, Triggiani M, Niedoszytko M, Schwartz LB, Orfao A, Horny HP, Metcalfe DD, 
Eur. J. Clin. Invest.; 2007; 37(6); 435-53; 17537151

Abnormal cytokine production by circulating monocytes and dendritic cells of myeloid origin in ART-treated HIV-1+ patients relates to CD4+ T-cell reco

Almeida M, Cordero M, Almeida J, Orfao A, 
Curr. HIV Res.; 2007; 5(3); 325-36; 17504174

Discriminant function analysis as decision support system for the diagnosis of acute leukemia with a minimal four color screening panel and multiparam

Ratei R, Karawajew L, Lacombe F, Jagoda K, Del Poeta G, Kraan J, de Santiago M, Kappelmayer J, Björklund E, Ludwig WD, Gratama JW, Orfao A, , 
Leukemia; 2007; 21(6); 1204-11; 17410192

Chronic alcohol consumption is associated with changes in the distribution, immunophenotype, and the inflammatory cytokine secretion profile of circul

Laso FJ, Vaquero JM, Almeida J, Marcos M, Orfao A, 
Alcohol. Clin. Exp. Res.; 2007; 31(5); 846-54; 17386065

Association between the HLA haplotype and the TCR-Vbeta repertoire of anti-hCMV specific memory T-cells in immunocompetent healthy adults.

Rodríguez-Caballero A, García-Montero AC, Almeida J, Balanzategui A, Munoz-Criado S, Orfao A, 
Cytometry B Clin Cytom; 2007; 72(5); 371-9; 17328033

Monoclonal TCR-Vbeta13.1+/CD4+/NKa+/CD8-/+dim T-LGL lymphocytosis: evidence for an antigen-driven chronic T-cell stimulation origin.

Garrido P, Ruiz-Cabello F, Bárcena P, Sandberg Y, Cantón J, Lima M, Balanzategui A, González M, López-Nevot MA, Langerak AW, García-Montero AC, Almeida J, Orfao A, 
Blood; 2007; 109(11); 4890-8; 17303697

ZAP70 editorial: a follow-up to the special issue.

Marti G, Orfao A, Goolsby CL, 
Cytometry B Clin Cytom; 2007; 72(2); 94-5; 17285625

Production of inflammatory cytokines by peripheral blood monocytes in chronic alcoholism: relationship with ethanol intake and liver disease.

Laso FJ, Vaquero JM, Almeida J, Marcos M, Orfao A, 
Cytometry B Clin Cytom; 2007; 72(5); 408-15; 17266151

Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference.

Valent P, Horny HP, Bennett JM, Fonatsch C, Germing U, Greenberg P, Haferlach T, Haase D, Kolb HJ, Krieger O, Loken M, van de Loosdrecht A, Ogata K, Orfao A, Pfeilstöcker M, Rüter B, Sperr WR, Stauder R, Wells DA, 
Leuk. Res.; 2007; 31(6); 727-36; 17257673

Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-39

Brüggemann M, White H, Gaulard P, García-Sanz R, Gameiro P, Oeschger S, Jasani B, Ott M, Delsol G, Orfao A, Tiemann M, Herbst H, Langerak AW, Spaargaren M, Moreau E, Groenen PJ, Sambade C, Foroni L, Carter GI, Hummel M, Bastard C, Davi F, Delfau-Larue MH, Kneba M, van Dongen JJ, Beldjord K, Molina TJ, 
Leukemia; 2007; 21(2); 215-21; 17170730

Relationship between CD38 expression on peripheral blood T-cells and monocytes, and response to antiretroviral therapy: a one-year longitudinal study

Almeida M, Cordero M, Almeida J, Orfao A, 
Cytometry B Clin Cytom; 2007; 72(1); 22-33; 17051525

Quantitative analysis of the expression of glycosylphosphatidylinositol-anchored proteins during the maturation of different hematopoietic cell compar

Hernández-Campo PM, Almeida J, Matarraz S, de Santiago M, Sanchez ML, Orfao A, 
Cytometry B Clin Cytom; 2007; 72(1); 34-42; 17051524

Sustained leukaemic phenotype after inactivation of BCR-ABLp190 in mice.

Pérez-Caro M, Gutierrez-Cianca N, González-Herrero I, López-Hernández I, Flores T, Orfao A, Sánchez-Martín M, Gutiérrez-Adán A, Pintado B, Sánchez-García I, 
Oncogene; 2007; 26(12); 1702-13; 16983340

Standardization of cell analysis methods in clinical cellular therapy programs: A challenge for ISCT.

Gratama J, Kvalheim G, Orfao A, 
Cytotherapy; 2006; 8(6); 528-9; 17148028

Clinical benefit associated with idiotypic vaccination in patients with follicular lymphoma.

Inogés S, Rodríguez-Calvillo M, Zabalegui N, López-Díaz de Cerio A, Villanueva H, Soria E, Suárez L, Rodríguez-Caballero A, Pastor F, García-Muñóz R, Panizo C, Pèrez-Calvo J, Melero I, Rocha E, Orfao A, Bendandi M, , 
J. Natl. Cancer Inst.; 2006; 98(18); 1292-301; 16985248

Impact of BCR/ABL gene expression on the proliferative rate of different subpopulations of haematopoietic cells in chronic myeloid leukaemia.

Primo D, Flores J, Quijano S, Sanchez ML, Sarasquete ME, del Pino-Montes J, Gaarder PI, González M, Orfao A, 
Br. J. Haematol.; 2006; 135(1); 43-51; 16939497

Flow cytometric analysis of normal and neoplastic mast cells: role in diagnosis and follow-up of mast cell disease.

Escribano L, Garcia Montero AC, Núñez R, Orfao A, , 
Immunol Allergy Clin Nort; 2006; 26(3); 535-47; 16931292

ZAP-70 in CLL: towards standardization of a biomarker for patient management: history of clinical cytometry special issue.

Marti G, Orfao A, Goolsby C, 
Cytometry B Clin Cytom; 2006; 70(4); 197-200; 16906575

Calcium-pH crosstalks in the human mast cell line HMC-1: intracellular alkalinization activates calcium extrusion through the plasma membrane Ca2+-ATP

Pernas-Sueiras O, Alfonso A, Vieytes MR, Orfao A, Escribano L, Francisca SJ, Botana LM, 
J. Cell. Biochem.; 2006; 99(5); 1397-408; 16817237

Microarray-based analysis of spinal versus intracranial meningiomas: different clinical, biological, and genetic characteristics associated with disti

Sayagués JM, Tabernero MD, Maíllo A, Trelles O, Espinosa AB, Sarasquete ME, Merino M, Rasillo A, Vera JF, Santos-Briz A, de Alava E, Garcia-Macias MC, Orfao A, 
J. Neuropathol. Exp. Neur; 2006; 65(5); 445-54; 16772868

Conventional diagnostics in multiple myeloma.

San Miguel JF, Gutiérrez NC, Mateo G, Orfao A, 
Eur. J. Cancer; 2006; 42(11); 1510-9; 16762540

KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Netwo

García-Montero AC, Jara-Acevedo M, Teodosio C, Sanchez ML, Nunez R, Prados A, Aldanondo I, Sanchez L, Domínguez M, Botana LM, Sanchez-Jimenez F, Sotlar K, Almeida J, Escribano L, Orfao A, 
Blood; 2006; 108(7); 2366-72; 16741248

Androgen-replacement therapy depresses the ex vivo production of inflammatory cytokines by circulating antigen-presenting cells in aging type-2 diabet

Corrales JJ, Almeida M, Burgo R, Mories MT, Miralles JM, Orfao A, 
J. Endocrinol.; 2006; 189(3); 595-604; 16731790

A new automated flow cytometry data analysis approach for the diagnostic screening of neoplastic B-cell disorders in peripheral blood samples with abs

Costa ES, Arroyo ME, Pedreira CE, García-Marcos MA, Tabernero MD, Almeida J, Orfao A, 
Leukemia; 2006; 20(7); 1221-30; 16728986

Persistent abnormalities in peripheral blood dendritic cells and monocytes from HIV-1-positive patients after 1 year of antiretroviral therapy.

Almeida M, Cordero M, Almeida J, Orfao A, 
J. Acquir. Immune Defic. ; 2006; 41(4); 405-15; 16652047

Heterogeneity of neoplastic cells in B-cell chronic lymphoproliferative disorders: biclonality versus intraclonal evolution of a single tumor cell clo

Sanchez ML, Almeida J, López A, Sayagués JM, Rasillo A, Sarasquete EA, Balanzategui A, Tabernero MD, Díaz-Mediavilla J, Barrachina C, Paiva A, González M, San Miguel JF, Orfao A, 
Haematologica; 2006; 91(3); 331-9; 16531256

Accurate apoptosis measurement requires quantification of loss of expression of surface antigens and cell fragmentation.

Diaz D, Prieto A, Barcenilla H, Monserrat J, Sánchez MA, Reyes E, Hernandez-Fuentes MP, de la Hera A, Orfao A, Alvarez-Mon M, 
Cytometry A; 2006; 69(4); 240-8; 16528734

Normal patterns of expression of glycosylphosphatidylinositol-anchored proteins on different subsets of peripheral blood cells: a frame of reference f

Hernández-Campo PM, Almeida J, Sanchez ML, Malvezzi M, Orfao A, 
Cytometry B Clin Cytom; 2006; 70(2); 71-81; 16493662

Lineage involvement in chronic myeloid leukaemia: comparison between MBCR/ABL and mBCR/ABL cases.

Primo D, Sanchez ML, Espinosa AB, Tabernero MD, Rasillo A, Sayagués JM, González M, Hernández JM, Orfao A, 
Br. J. Haematol.; 2006; 132(6); 736-9; 16487173

Characterization of bone marrow T cells in monoclonal gammopathy of undetermined significance, multiple myeloma, and plasma cell leukemia demonstrates

Pérez-Andrés M, Almeida J, Martín-Ayuso M, Moro MJ, Martín-Nuñez G, Galende J, Hernandez J, Mateo G, San Miguel JF, Orfao A, , 
Cancer; 2006; 106(6); 1296-305; 16475149

The cytogenetic relationship between primary and recurrent meningiomas points to the need for new treatment strategies in cases at high risk of relaps

Espinosa AB, Tabernero MD, Maíllo A, Sayagués JM, Ciudad J, Merino M, Alguero MC, Lubombo AM, Sousa P, Santos-Briz A, Orfao A, 
Clin. Cancer Res.; 2006; 12(3 Pt 1); 772-80; 16467088

Near-tetraploid acute myeloid leukemias: an EGIL retrospective study of 25 cases.

Béné MC, Castoldi G, Derolf A, Garand R, Haas T, Haferlach T, Knapp W, Kuhlein E, Lemez P, Ludwig WD, Marinov I, Matutes E, Michalová K, Porwit-MacDonald A, Orfao A, Schoch C, Talmant P, Van't Veer MB, Zemanová Z, Zühlsdorf M, , 
Leukemia; 2006; 20(4); 725-8; 16437146

TCRgammadelta+ large granular lymphocyte leukemias reflect the spectrum of normal antigen-selected TCRgammadelta+ T-cells.

Sandberg Y, Almeida J, González M, Lima M, Bárcena P, Szczepañski T, van Gastel-Mol EJ, Wind H, Balanzategui A, van Dongen JJ, Miguel JF, Orfao A, Langerak AW, 
Leukemia; 2006; 20(3); 505-13; 16437145

Report on the second Latin American consensus conference for flow cytometric immunophenotyping of hematological malignancies.

Ruiz-Argüelles A, Rivadeneyra-Espinoza L, Duque RE, Orfao A, , 
Cytometry B Clin Cytom; 2006; 70(1); 39-44; 16353215

Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduce

Bendandi M, Rodríguez-Calvillo M, Inogés S, López-Díaz de Cerio A, Perez-Simon JA, Rodríguez-Caballero A, García-Montero A, Almeida J, Zabalegui N, Giraldo P, San Miguel J, Orfao A, 
Leuk. Lymphoma; 2006; 47(1); 29-37; 16321824

Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias.

Ratei R, Karawajew L, Lacombe F, Jagoda K, Del Poeta G, Kraan J, de Santiago M, Kappelmayer J, Björklund E, Ludwig WD, Gratama J, Orfao A, , 
Cytometry B Clin Cytom; 2006; 70(1); 1-9; 16278833

Minimal residual disease monitoring in multiple myeloma: a comparison between allelic-specific oligonucleotide real-time quantitative polymerase chain

Sarasquete ME, García-Sanz R, González D, Martínez J, Mateo G, Martínez P, Ribera JM, Hernández JM, Lahuerta JJ, Orfao A, González M, San Miguel JF, 
Haematologica; 2005; 90(10); 1365-72; 16219573

Cancer development induced by graded expression of Snail in mice.

Pérez-Mancera PA, Pérez-Caro M, González-Herrero I, Flores T, Orfao A, de Herreros AG, Gutiérrez-Adán A, Pintado B, Sagrera A, Sánchez-Martín M, Sánchez-García I, 
Hum. Mol. Genet.; 2005; 14(22); 3449-61; 16207734

[Immune system and alcoholic liver disease].

Laso FJ, Pastor I, Orfao A, 
Med Clin (Barc); 2005; 125(7); 263-9; 16137488

Posttransplant hematopoiesis in patients undergoing sibling allogeneic stem cell transplantation reflects that of their respective donors although wit

Sanchez-Guijo FM, Sanchez-Abarca LI, Villaron E, Lopez-Holgado N, Alberca M, Vazquez L, Perez-Simon JA, Lopez-Fidalgo J, Orfao A, Caballero MD, del Cañizo MC, San Miguel JF, 
Exp. Hematol.; 2005; 33(8); 935-43; 16038787

Imatinib is not a potential alternative treatment for uterine leiomyosarcoma.

Serrano C, Mackintosh C, Herrero D, Martins AS, de Alava E, Hernández T, Pérez-Fontán J, Abad M, Pérez A, Serrano E, Bullón A, Orfao A, 
Clin. Cancer Res.; 2005; 11(13); 4977-9; ; 16000598

Characterization of chromosome 14 abnormalities by interphase in situ hybridization and comparative genomic hybridization in 124 meningiomas: correlat

Tabernero MD, Espinosa AB, Maíllo A, Sayagués JM, Alguero Mdel C, Lumbreras E, Díaz P, Gonçalves JM, Onzain I, Merino M, Morales F, Orfao A, 
Am. J. Clin. Pathol.; 2005; 123(5); 744-51; 15981814

Discrimination of biclonal B-cell chronic lymphoproliferative neoplasias by tetraspanin antigen expression.

Barrena S, Almeida J, Yunta M, López A, Díaz-Mediavilla J, Orfao A, Lazo PA, 
Leukemia; 2005; 19(9); 1708-9; 15973446

Aberrant expression of tetraspanin molecules in B-cell chronic lymphoproliferative disorders and its correlation with normal B-cell maturation.

Barrena S, Almeida J, Yunta M, López A, Fernández-Mosteirín N, Giralt M, Romero M, Perdiguer L, Delgado M, Orfao A, Lazo PA, 
Leukemia; 2005; 19(8); 1376-83; 15931266

Genetic abnormalities and patterns of antigenic expression in multiple myeloma.

Mateo G, Castellanos M, Rasillo A, Gutiérrez NC, Montalbán MA, Martín ML, Hernández JM, López-Berges MC, Montejano L, Bladé J, Mateos MV, Sureda A, de la Rubia J, Díaz-Mediavilla J, Pandiella A, Lahuerta JJ, Orfao A, San Miguel JF, 
Clin. Cancer Res.; 2005; 11(10); 3661-7; 15897562

Long-term immune recovery of patients undergoing allogeneic stem cell transplantation: a comparison with their respective sibling donors.

Sanchez-Guijo FM, Sanchez-Abarca LI, Bueno C, Villaron E, Lopez-Holgado N, Vazquez L, Lopez-Fidalgo J, Perez-Simon JA, Caballero MD, del Cañizo MC, Orfao A, San Miguel JF, 
Biol. Blood Marrow Transp; 2005; 11(5); 354-61; 15846289

Analytic performance of the PENTRA 80 automated blood cell analyzer for the evaluation of normal and pathologic WBCs.

Arroyo ME, Tabernero MD, García-Marcos MA, Orfao A, 
Am. J. Clin. Pathol.; 2005; 123(2); 206-14; 15842044

Genetic heterogeneity of BCR/ABL+ adult B-cell precursor acute lymphoblastic leukemia: impact on the clinical, biological and immunophenotypical disea

Primo D, Tabernero MD, Perez JJ, Rasillo A, Sayagués JM, Espinosa AB, López-Berges MC, García-Sanz R, Gutiérrez NC, Hernández JM, Romero M, Osuna CS, Giralt M, Barbon M, San Miguel JF, Orfao A, 
Leukemia; 2005; 19(5); 713-20; 15789066

Evaluation of multiparameter flow cytometry for the detection of breast cancer tumor cells in blood samples.

Cruz I, Ciudad J, Cruz JJ, Ramos M, Gómez-Alonso A, Adansa JC, Rodríguez C, Orfao A, 
Am. J. Clin. Pathol.; 2005; 123(1); 66-74; 15762281

Different subsets of peripheral blood dendritic cells show distinct phenotypic and functional abnormalities in HIV-1 infection.

Almeida M, Cordero M, Almeida J, Orfao A, 
AIDS; 2005; 19(3); 261-71; 15718836

Clonal plasma cells from monoclonal gammopathy of undetermined significance, multiple myeloma and plasma cell leukemia show different expression profi

Pérez-Andrés M, Almeida J, Martín-Ayuso M, Moro MJ, Martín-Nuñez G, Galende J, Borrego D, Rodríguez MJ, Ortega F, Hernandez J, Moreno I, Domínguez M, Mateo G, San Miguel JF, Orfao A, , 
Leukemia; 2005; 19(3); 449-55; 15674420

Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation o

Suárez L, Vidriales MB, Moreno MJ, López A, García-Laraña J, Pérez-López C, Tormo M, Lavilla E, López-Berges MC, de Santiago M, San Miguel JF, Orfao A, , 
Haematologica; 2005; 90(1); 54-9; 15642669

A new simple whole blood flow cytometry-based method for simultaneous identification of activated cells and quantitative evaluation of cytokines relea

Rodríguez-Caballero A, García-Montero AC, Bueno C, Almeida J, Varro R, Chen R, Pandiella A, Orfao A, 
Lab Invest; 2004; 84(10); 1387-98; 15311213

Flow cytometric analysis of cytokine responses in stimulated whole blood: simultaneous quantitation of TNF-alpha-secreting cells and soluble cytokines

Rodríguez-Caballero A, García-Montero A, Bueno C, Orfao A, 
Curr Protoc Cytom; 2003; Chapter 9(; Unit 9.2; 18770784

A new method for detecting TNF-alpha-secreting cells using direct-immunofluorescence surface membrane stainings.

Bueno C, Rodríguez-Caballero A, García-Montero A, Pandiella A, Almeida J, Orfao A, 
J Immunol Methods; 2002; 264(1-2); 77-87; 12191512

Comparative analysis of the morphological, cytochemical, immunophenotypical, and functional characteristics of normal human peripheral blood lineage(-

Almeida J, Bueno C, Alguero MC, Sanchez ML, de Santiago M, Escribano L, Díaz-Agustín B, Vaquero JM, Laso FJ, San Miguel JF, Orfao A, 
Clin Immunol; 2001; 100(3); 325-38; 11513546

Flow cytometric analysis of cytokine production by normal human peripheral blood dendritic cells and monocytes: comparative analysis of different stim

Bueno C, Almeida J, Alguero MC, Sanchez ML, Vaquero JM, Laso FJ, San Miguel JF, Escribano L, Orfao A, 
Cytometry; 2001; 46(1); 33-40; 11241505

Extensive characterization of the immunophenotype and pattern of cytokine production by distinct subpopulations of normal human peripheral blood MHC I

Almeida J, Bueno C, Alguero MC, Sanchez ML, Cañizo MC, Fernandez ME, Vaquero JM, Laso FJ, Escribano L, San Miguel JF, Orfao A, 
Clin Exp Immunol; 1999; 118(3); 392-401; 10594557

Genomics and proteomics approaches for biomarker discovery in sporadic colorectal cancer with metastasis.

González-González M, Garcia JG, Montero JA, Fernandez LM, Bengoechea O, Muñez OB, Orfao A, Sayagués JM, Fuentes M, 
Cancer Genomics Proteomic; -; 10(1); 19-25; 23382583

CD203c is overexpressed on neoplastic mast cells in systemic mastocytosis and is upregulated upon IgE receptor cross-linking.

Hauswirth AW, Escribano L, Prados A, Núñez R, Mirkina I, Kneidinger M, Florian S, Sonneck K, Vales A, Schernthaner GH, Sánchez-Muñoz L, Sperr WR, Bühring HJ, Orfao A, Valent P, 
Int J Immunopathol Pharma; -; 21(4); 797-806; 19144265

Decreased production of inflammatory cytokines by circulating monocytes and dendritic cells in type 2 diabetic men with atherosclerotic complications.

Corrales JJ, Almeida M, Burgo RM, Hernández P, Miralles JM, Orfao A, 
J. Diabetes Complicat.; -; 21(1); 41-9; 17189873

Reactive phenotypes after acute and chronic NK-cell activation.

Lima M, Almeida J, Teixeira MA, Santos AH, Queirós ML, Fonseca S, Moura J, Gonçalves M, Orfao A, Pinto Ribeiro AC, 
J. Biol. Regul. Homeost. ; -; 18(3-4); 331-4; 15786700

Intrinsically fluorescent cytotoxic cisplatin analogues as DNA marker molecules.

Criado JJ, Fernández ER, Manzano JL, Alonso A, Barrena S, Medarde M, Peláez R, Tabernero MD, Orfao A, 
Bioconjug. Chem.; -; 16(2); 275-82; 15769080

Affinity binding of cells to cryogel adsorbents with immobilized specific ligands: effect of ligand coupling and matrix architecture.

Kumar A, Rodríguez-Caballero A, Plieva FM, Galaev IY, Nandakumar KS, Kamihira M, Holmdahl R, Orfao A, Mattiasson B, 
J. Mol. Recognit.; -; 18(1); 84-93; 15386616

Casabonne D, Almeida J, Nieto WG, Romero A, Fernández-Navarro P, Rodríguez-Caballero A, Muñoz-Criado S, Díaz MG, Benavente Y, de Sanjosé S, Orfao A, 
; ; ; ; 24146721

Paiva B, Montes MC, García-Sanz R, Ocio EM, Alonso J, de Las Heras N, Escalante F, Cuello R, de Coca AG, Galende J, Hernandez J, Sierra M, Martín A, Pardal E, Bárez A, Suárez L, González-López TJ, Perez JJ, Orfao A, Vidriales MB, San Miguel JF, 
; ; ; ; 23604227

Morgado JM, Sánchez-Muñoz L, Teodósio CG, Jara-Acevedo M, Alvarez-Twose I, Matito A, Fernández-Nuñez E, García-Montero A, Orfao A, Escribano L, 
; ; ; ; 22222639

García-Sanz R, Ocio E, Caballero A, Magalhães RJ, Alonso J, López-Anglada L, Villaescusa T, Puig N, Hernández JM, Fernández-Calvo J, Aguilar A, Martín A, López R, Paiva B, Orfao A, Vidriales B, San-Miguel JF, Del Carpio D, 
; ; ; ; 21856552

Ternavasio-de la Vega HG, Velasco-Tirado V, Pozo-Rosado L, Soler-Fernández MC, Pérez-Andrés M, Orfao A, Sánchez-Sánchez R, González-Villaron L, 
; ; ; ; 21520407

Sancho JM, Orfao A, Quijano S, García O, Panizo C, Pérez-Ceballos E, Debén G, Salar A, González-Barca E, Alonso N, García-Vela JA, Capote J, Peñalver FJ, Provencio M, Arias J, Plaza J, Caballero D, Morado M, Feliu E, Ribera JM, 
; ; ; ; 20528905

Quijano S, López A, Manuel Sancho J, Panizo C, Debén G, Castilla C, Antonio García-Vela J, Salar A, Alonso-Vence N, González-Barca E, Peñalver FJ, Plaza-Villa J, Morado M, García-Marco J, Arias J, Briones J, Ferrer S, Capote J, Nicolás C, Orfao A, 
; ; ; ; 19224854

Ocio EM, Mateo G, Vidriales B, López-Berges MC, García-Sanz R, Hernández JM, Orfao A, San Miguel JF, 
; ; ; ; 15794858

Ocio EM, Hernández JM, Mateo G, Sanchez ML, Gonzalez B, Vidriales B, Gutiérrez NC, Orfao A, San Miguel JF, 
; ; ; ; 15794856