Centro de Investigación del Cáncer (Universidad de Salamanca-CSIC)
Campus Universitario Miguel de Unamuno s/n
37007 Salamanca
SPAIN
Instituto de Salud Carlos III (2013-2015)
Interacciones entre las células de mieloma y estroma de la médula ósea: papel en la progresión de las gammapatías asistomáticas, fisiopatología y lesiones osteolíticas del mieloma múltiple.
Insituto de Salud Carlos III (2009-2011)
Estudio de la eficacia y mecanismo de acción de nuevos fármacos anti-mieloma con especial incidencia sobre el microambiente de la médula osea
Junta de Castilla y León (2008-2008)
“Potencial osteogénicos de las células progenitores mesenquimales de la médula ósea de pacientes con mieloma múltiple”
INSTITUTO DE SALUD CARLOS III (2006-2009)
EL MICROAMBIENTE DE LA MEDULA OSEA EN EL MIELOMA MULTIPLE: "INFLUENCIA EN LA PROLIFERACION DE LAS CELULAS DE MIELOMA Y EN LA RESPUESTA A DISTINTOS FARMACOS"
(*) Means equal contribution as senior authors.
Hernandez-Garcia S, San-Segundo L, González-Méndez L, Corchete LA, Misiewicz-Krzeminska I, Martín-Sánchez M, López-Iglesias AA, Algarín EM, Mogollón P, Díaz-Tejedor A, Paíno T, Tunquist B, Mateos MV, Gutiérrez NC, Díaz-Rodríguez E, Garayoa M, Ocio EM, Haematologica; 2017; 102(12); 2113-212; 28860344
López-Iglesias AA, Herrero AB, Chesi M, San-Segundo L, González-Méndez L, Hernandez-Garcia S, Misiewicz-Krzeminska I, Quwaider D, Martín-Sánchez M, Primo D, Paíno T, Bergsagel PL, Mehrling T, Gonzalez-Diaz M, San-Miguel JF, Mateos MV, Gutiérrez NC, Garayoa M, Ocio EM, J Hematol Oncol; 2017; 10(1); 127; 28633670
Ocio EM, Fernández-Lázaro D, San-Segundo L, López-Corral L, Corchete LA, Gutiérrez NC, Garayoa M, Paíno T, Garcia-Gomez A, Delgado M, Montero JC, Díaz-Rodríguez E, Mateos MV, Pandiella A, Couto S, Wang M, Bjorklund CC, San-Miguel JF, Leukemia; 2015; 29(3); 705-14; 25102946
Garcia-Gomez A, De Las Rivas J, Ocio EM, Díaz-Rodríguez E, Montero JC, Martín M, Blanco JF, Sanchez-Guijo FM, Pandiella A, San Miguel JF, Garayoa M, Oncotarget; 2014; 5(18); 8284-305; 25268740
Paiva B, Paíno T, Sayagués JM, Garayoa M, San-Segundo L, Martín M, Mota I, Sanchez ML, Bárcena P, Aires-Mejia I, Corchete L, Jimenez C, García-Sanz R, Gutiérrez NC, Ocio EM, Mateos MV, Vidriales MB, Orfao A, San Miguel JF, Blood; 2013; 122(22); 3591-8; 24072855
Garcia-Gomez A, Ocio EM, Pandiella A, San Miguel JF, Garayoa M, Invest New Drugs; 2013; 31(1); 200-5; 22773056
Hurchla MA, Garcia-Gomez A, Hornick MC, Ocio EM, Li A, Blanco JF, Collins L, Kirk CJ, Piwnica-Worms D, Vij R, Tomasson MH, Pandiella A, San Miguel JF, Garayoa M, Weilbaecher KN, Leukemia; 2013; 27(2); 430-40; 22763387
Garcia-Gomez A, Ocio EM, Crusoe E, Santamaria C, Hernandez-Campo P, Blanco JF, Sanchez-Guijo FM, Hernández-Iglesias T, Briñón JG, Fisac-Herrero RM, Lee FY, Pandiella A, San Miguel JF, Garayoa M, PLoS ONE; 2012; 7(4); e34914; 22539950
Paíno T, Ocio EM, Paiva B, San-Segundo L, Garayoa M, Gutiérrez NC, Sarasquete ME, Pandiella A, Orfao A, San Miguel JF, Haematologica; 2012; 97(7); 1110-4; 22315496
Colado E, Paíno T, Maiso P, Ocio EM, Chen X, Alvarez-Fernández S, Gutiérrez NC, Martín-Sánchez J, Flores-Montero J, San Segundo L, Garayoa M, Fernández-Lázaro D, Vidriales MB, Galmarini CM, Aviles P, Cuevas C, Pandiella A, San-Miguel JF, Haematologica; 2011; 96(5); 687-95; 21330323
Ocio EM, Vilanova D, Atadja P, Maiso P, Crusoe E, Fernández-Lázaro D, Garayoa M, San-Segundo L, Hernández-Iglesias T, de Alava E, Shao W, Yao YM, Pandiella A, San-Miguel JF, Haematologica; 2010; 95(5); 794-803; 19951978
Maiso P, Colado E, Ocio EM, Garayoa M, Martín J, Atadja P, Pandiella A, San-Miguel JF, Leukemia; 2009; 23(12); 2265-74; 19812608
Garayoa M, García JL, Santamaria C, Garcia-Gomez A, Blanco JF, Pandiella A, Hernández JM, Sanchez-Guijo FM, del Cañizo MC, Gutiérrez NC, San Miguel JF, Leukemia; 2009; 23(8); 1515-27; 19357701
Ocio EM, Maiso P, Chen X, Garayoa M, Alvarez-Fernández S, San-Segundo L, Vilanova D, López-Corral L, Montero JC, Hernández-Iglesias T, de Alava E, Galmarini C, Aviles P, Cuevas C, San-Miguel JF, Pandiella A, Blood; 2009; 113(16); 3781-91; 19020308
Mitsiades CS, Ocio EM, Pandiella A, Maiso P, Gajate C, Garayoa M, Vilanova D, Montero JC, Mitsiades N, McMullan CJ, Munshi NC, Hideshima T, Chauhan D, Aviles P, Otero G, Faircloth G, Mateos MV, Richardson PG, Mollinedo F, San-Miguel JF, Anderson KC, Cancer Res.; 2008; 68(13); 5216-25; 18593922
Maiso P, Ocio EM, Garayoa M, Montero JC, Hofmann F, García-Echeverría C, Zimmermann J, Pandiella A, San Miguel JF, Br J Haematol; 2008; 141(4); 470-82; 18341634
Colado E, Alvarez-Fernández S, Maiso P, Martín-Sánchez J, Vidriales MB, Garayoa M, Ocio EM, Montero JC, Pandiella A, San Miguel JF, Haematologica; 2008; 93(1); 57-66; 18166786
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Email: lacorsan@hotmail.com
Research group in Molecular Cytogenetics
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Email: jmhr@usal.es
This group is focused in the cytogenetics and molecular characterization of cancer.
The scientific contribution of this line of research is competitive and internationally renowed. The main lines of research being developed are the following:
A) Expression profiling by high-density microarrays and next generation sequencing of hematological malignancies.
B) Methylation and miRNA patterns of solid tumours.
C) Pharmacogenomics of new drugs used in cancer therapy.
The challenges of the group will be the integration of the data obtained oin the different research lines in order to provide a personalized medicina in cancer therapy. In addition, the implementation of all of these new tools, including next generation sequencing and the translation to the clinical setting is also a main goal of the group.
×Telf.:
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Email: fernandolobato@usal.es
multiple myeloma, biomarkers, proteins, miRNA, mRNA splicing
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Email: irenamk@usal.es
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Email: adrianmo18@gmail.com
After graduating in Biotechnology (2015) at the University of Cádiz (Spain), I started my scientific career at the Cancer Research Center-University of Salamanca(Spain), under the supervision of Professor Dr Jesús M. Hernández Rivas, developing the master degree "Biología y clínica del cáncer". I began my PhD studies in 2016 supported by a Predoctoral Grant from Asociación Española Contra el Cáncer (AECC), working on the study of B Acute Lymphoblastic Leukemia (B-ALL). This project is mainly based on the study of patient samples through the use of NGS technology and the generation of genetically modified models, both in vitro and in vivo.
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Email: navasajosgrey@javeriana.edu.co